OBJECTIVE To evaluate the suppressive effect of electric cortical stimulation upon the seizure onset zone and the non-epileptic cortex covered by subdural electrodes in patients with neocortical epilepsy and mesial temporal lobe epilepsy (MTLE). METHODS Four patients with medically intractable focal epilepsy had implanted subdural electrodes for preoperative evaluation. Cortical functional ma...

We demonstrate an easy-to-manufacture 25-mm-long ultra-stable optical reference cavity for transportable photonic microwave generation systems. Employing a rigid holding geometry that is first-order insensitive to the squeezing force and a cavity geometry that improves the thermal noise limit at room temperature, we observe a laser phase noise that is nearly thermal noise limited for three freq...

During drowsiness, human performance in responding to above-threshold auditory targets tends to vary irregularly over periods of 4 min and longer. These performance fluctuations are accompanied by distinct changes in the frequency spectrum of the electroencephalogram (EEG) on three time scales: (1) during minute-scale and longer periods of intermittent responding, mean activity levels in the (<...

In simulations of electrical-acoustic stimulation (EAS), vocoded speech intelligibility is aided by preservation of low-frequency acoustic cues. However, the speech signal is often interrupted in everyday listening conditions, and effects of interruption on hybrid speech intelligibility are poorly understood. Additionally, listeners rely on information-bearing acoustic changes to understand ful...

The after-effects of locomotor stimulation are a transient facilitation of locomotor initiation (the priming effect), and a transient increase in hippocampal rhythmic slow activity in the 3–6 Hz band of the theta range. The similar time course of the two effects suggests that hippocampal 3–6 Hz activity may be linked to the excitability of locomotor initiation. This study tested the hypothesis ...

The repetitive nerve stimulation test (RNST) has been a useful method in the diagnosis of myasthenia gravis (MG). In clinical practice, a short train of repetitive stimulation is usually given at 3 Hz. Although it was documented that lower stimulation frequencies could offer a greater sensitivity, no study has been done to testify the most sensitive stimulation frequency for RNST. To find out a...

Mouse full-field electroretinograms (ERGs) are dominated by responses of photoreceptors and depolarizing (ON-) bipolar cells, but not much of hyperpolarizing (OFF-) bipolar cells under conventional recording conditions. Here we investigate a novel ERG protocol in mice for functional assessment of the major ON- and OFF-bipolar cell pathways using flicker stimuli for a high luminance with varying...

OBJECTIVE The aim of this study was to explore the frequency response of visually induced motion sickness (VIMS) for oscillating linear motion in the fore-and-aft axis. BACKGROUND Simulators, virtual environments, and commercially available video games that create an illusion of self-motion are often reported to induce the symptoms seen in response to true motion. Often this human response ca...

2014 An elastic dilatational mode at very low frequency (20-2 000 Hz) in a gel rod is used to deflect a laser beam in a simple and very low price set-up. A 15° deflection is observed at 140 Hz with a electrical power of 9 mW. Revue Phys. Appl. 15 (1980) 875-878 AVRIL 1980, Classification Physics Abstracts 07.60 42.80 81.20S .

Excessive synchronization of basal ganglia neural activity at low frequencies is considered a hallmark of Parkinson's disease (PD). However, few studies have unambiguously linked this activity to movement impairment through direct stimulation of basal ganglia targets at low frequency. Furthermore, these studies have varied in their methodology and findings, so it remains unclear whether stimula...