Methods: Thirty-two male Wistar rats were divided into thre groups as follows: group 1, non-treatment group; group 2, EHEN alone group; group3, EHEN+apocynin group. Groups 2 and 3 were administered 500 ppm EHEN in their drinking water for the first 2 weeks. After the EHEN treatment, group 3 were treated with 15 mg/kg BW apocynin 5 times a week for 30 weeks. At the end of experiment week 32, his...

Concerns exist as to whether individuals may be at greater risk for neurotoxicity following increased manganese (Mn) oral intake. The goals of this study were to determine the equivalence of 3 methods of oral exposure and the rate (mg Mn/kg/day) of exposure. Adult male rats were allocated to control diet (10 ppm), high manganese diet (200 ppm), manganese-supplemented drinking water, and mangane...

T HE DENTAL benefits from drinking water containing about 1 part per million (1 ppm = 1 mg/I) of fluoride ion during childhood are well known. The safety of adjusting public supplies of drinking water to this content of fluoride in temperate climates (or to about 0.7 ppm in hotter areas) is universally accepted among reputable professional groups with an interest in the problem of dental caries...

A liquid chromatography/mass spectrometry (LC/MS) method is developed for the fast, high throughput quantitation of acrylamide in drinking water using online sample extraction coupled with the Agilent liquid chromatography/mass selective detector time-of-flight (LC/MSD TOF). The limit of quantitation of 0.25 μg/L meets the World Health Organization guideline for the maximum safe level concentra...

Halogenated hydrocarbons such as trichloroethylene (TCE) are among the most common water supply contaminants in the United States and abroad. Epidemiologic studies have found an association but not a cause-and-effect relation between halogenated hydrocarbon contamination and increased incidence of congenital cardiac malformations or other defective birth outcomes. Avian and rat studies demonstr...

this study was conducted to assay the use of saturejahortensis l. (savory) essential oil in the drinking water on broiler production and blood glucose, uric acid, creatinin and cholesterol. four hundred and twenty day old broiler chickens (ross 308) was used in a completely randomized design with 6 treatments and 5 replicate. experimental treatments included: 1) control, 2) tween (a solvent for...

Chronic Toxicity and Three-Generation Reproduction Study of Styrene Monomer in the Drinking Water of Rats. BELILES, R. P., BUTALA, J. H., STACK, C. R., AND MAKRIS, S. (1985). Fundam. Appl. Toxicol.. 5,855-868. Chronic toxicity and reproductive performance were evaluated in groups of rats receiving styrene monomer in their drinking water at nominal concentrations of 0, 125, or 250 ppm. Fifty mal...