Immunosuppression is an essential aspect of managing cardiac sarcoidosis (CS). The decision to implant a cardiovascular implantable electronic device (CIED) often made in conjunction with starting immunosuppression. It unclear if immunosuppression at the time implantation increases risk CIED infections. Since both are potentially life-saving therapies for CS, it vital understand there need adju...

declarator, 181, 1190access-specifier, 231, 1192additive-expression, 118, 1183alias-declaration, 139, 1186alignment-specifier, 175, 1189and-expression, 122, 1183asm-definition, 171, 1188assignment-expression, 125, 1184assignment-operator, 125, 1184attribute, 175, 1189attribute-argument-clause, 175, 1189attribute-declaration, 139, 1186attribute-lis...

We have previously shown that amyotrophic lateral sclerosis with cognitive impairment can be characterized by pathologic inclusions of microtubule-associated protein tau (tau) phosphorylated at Thr(175) (pThr(175)) in association with GSK3β activation. We have now examined whether pThr(175) induces GSK3β activation and whether this leads to pathologic fibril formation through Thr(231) phosphory...

Plasmodium falciparum malaria merozoites invade human erythrocytes bearing sialic acid in a multistage process involving the sialic acid-dependent binding of a malaria molecule, the 175-kD erythrocyte binding antigen (EBA-175). We show here that after the initial interaction of EBA-175 with its sialic acid-containing erythrocyte determinant, endogenous proteases can cleave EBA-175 to 65-kD frag...