نتایج جستجو برای: 18 18f

تعداد نتایج: 361982  

Objective(s): The study objective was to assess the diagnostic performance of positron emission tomography (PET) for gliomas using the novel tracer 18F-fluciclovine (anti-[18F]FACBC) and to evaluate the safety of this tracer in patients with clinically suspected gliomas.Methods: Anti-[18F]FACBC was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by PET...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Ronnie C Mease Crystal L Dusich Catherine A Foss Hayden T Ravert Robert F Dannals Jurgen Seidel Andrew Prideaux James J Fox George Sgouros Alan P Kozikowski Martin G Pomper

PURPOSE Previously, we showed successful imaging of xenografts that express the prostate-specific membrane antigen (PSMA) using small-animal positron emission tomography (PET) and the radiolabeled PSMA inhibitor N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-S-[11C]methyl-l-cysteine. Herein, we extend that work by preparing and testing a PSMA inhibitor of the same class labeled with fluorine-18. EX...

Journal: :iranian journal of nuclear medicine 0
babak fallahi research center for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran bahar moasses-ghafari research center for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran armaghan fard-esfahani research center for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran parham geramifar research center for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran davood beiki research center for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran alireza emami-ardekani research center for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran mohammad eftekhari

introduction:myocardial 18f-fdg uptake is highly variable in oncologic whole body 18f-fdg pet/ct studies, ranging from quite intense to minimal distribution. intense or heterogeneous myocardial 18f-fdg uptake is undesirable as it may interfere with the visual or quantitative evaluation of tumoral invasion and metastases in pericardium, myocardium or adjacent mediastinal structures. the diet, as...

2017
Ingrid Kreimerman Williams Porcal Silvia Olivera Patricia Oliver Eduardo Savio Henry Engler

BACKGROUND The red fluorescent dye Sulforhodamine 101 (SR101) has been used in neuroscience research as a useful tool for staining of astrocytes, since it has been reported as a marker of astroglia in the neocortex of rodents in vivo. The aim of this work is to label SR101 with positron emission radionuclides, in order to provide a radiotracer to study its biological behavior. This is the first...

2017
Madhurima R Chetan Tristan Barrett Ferdia A Gallagher

AIM To determine the significance and need for investigation of incidental prostatic uptake in men undergoing 18F-labelled fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for other indications. METHODS Hospital databases were searched over a 5-year period for patients undergoing both PET/CT and prostate magnetic resonance imaging (MRI). For the initial a...

2018
Javier Giglio Maia Zeni Eduardo Savio Henry Engler

Background Overexpression of prostatic membrane antigen (PSMA) is associated with the progression and prognosis of prostate cancer. There are numerous studies using this peptide with the 68Ga radionuclide. Previous methods to synthetize 18F-labeled PSMA ligands with complexes [18F]AlF2+ have been achieved. However, these reported syntheses were performed manually, using small volumes. Therefore...

2017
Kenji Ishibashi Airin Onishi Yoshinori Fujiwara Kiichi Ishiwata Kenji Ishii

BACKGROUND Increasing plasma glucose levels and insulin resistance can alter the distribution pattern of fluorine-18-labeled fluorodeoxyglucose (18F-FDG) in the brain and relatively reduce 18F-FDG uptake in Alzheimer's disease (AD)-related hypometabolic regions, leading to the appearance of an AD-like pattern. However, its relationship with plasma insulin levels is unclear. We aimed to compare ...

Journal: :Annals of nuclear medicine 2015
Gundula Rendl Lukas Rettenbacher Johannes Holzmannhofer Lidwina Datz Cornelia Hauser-Kronberger Gerd Fastner Dietmar Öfner Felix Sedlmayer Christian Pirich

OBJECTIVE The comparison of 2-deoxy-2-[18F]fluoro-D-glucose (F-18 FDG) and 3'-deoxy-3'-[18F]fluorothymidine (F-18 FLT) imaging in patients with rectal cancer before and after neoadjuvant radiochemotherapy (RCT) in relation to histopathology and immunohistochemistry obtained from surgery. METHODS 20 consecutive patients (15 m, 5 f), mean age of 65 ± 10 years were included into this prospective...

2016
Sang Don Kwon Kyung Ah Chun Eun Jung Kong Ihn Ho Cho

The authors report the case of a 34-year-old male, who underwent a fluorine-18 fluoro deoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan 7 years after trauma for the evaluation of multifocal masses in the right iliac and right inguinal areas. CT findings showed multifocal low density masses and 18F-FDG PET revealed slightly increased uptake (maximum standardiz...

2017
Thomas Lee Collier Steven H Liang J John Mann Neil Vasdev J S Dileep Kumar

Continuous-flow microfluidics has shown increased applications in radiochemistry over the last decade, particularly for both pre-clinical and clinical production of fluorine-18 labeled radiotracers. The main advantages of microfluidics are the reduction in reaction times and consumption of reagents that often result in increased radiochemical yields and rapid optimization of reaction parameters...

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