BACKGROUND Frontotemporal dementia (FTD) causes progressive change in activities of daily living (ADLs) and little is known about their rate of decline. This study aimed to examine changes in ADLs, including subcomponents of initiation, planning or execution. METHODS A total of 72 ADL and general cognitive assessments were analysed. The patients were subdivided into behavioural variant FTD (b...

Objective: Knowledge of risk factors for variant CJD (vCJD) remains limited, but transmission of prion proteins via re-useable medical devices, including dental instruments, or enhanced susceptibility following trauma to the oral cavity is a concern. This study aimed to identify whether previous dental treatment is a risk factor for development of vCJD. Design: Case control study Methods: Risk ...

The ubiquitin carboxyl-terminal esterase L1 gene, UCHL1, located on chromosome 4p14, has been studied as a potential candidate gene for Parkinson's disease risk. The authors conducted a Human Genome Epidemiology review and meta-analysis of published case-control studies of the UCHL1 S18Y variant and Parkinson's disease in Asian and Caucasian samples. The meta-analysis of studies in populations ...

Mannose-binding lectin (MBL) is one of the five recognition molecules in the lectin complement pathway. Common variant alleles in the promoter and structural regions of the human MBL gene (MBL2) influence the stability and serum concentration of the protein. Epidemiological studies have shown that MBL2 variant alleles are associated with susceptibility to and the course of different types of in...

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Background: RNA molecules play many important regulatory, catalytic and structural <span style="font-variant: normal; font-style: norma...

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After fullerene and nanotubes, graphene is a new allotrope of carbon. This attractive nanomaterial can be produced by different methods. In this work, <span style="font-size: 11pt; color: #000000; font...

The new UK variant of SARS-CoV-2 may be associated with an increased risk death, emerging data are suggesting. In a briefing paper published on 22 January the government’s New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) highlighted several preliminary analyses showing possible increase in severity disease concern (VOC) B.1.1.7, which first emerged Kent September.1 Two unpu...

Examination of the available ignition delay time data and correlations in the case of methane, butane, heptane, decane, kerosene, Jet-A and <span style="font-size: 12pt; color: #000000; font-style: nor...