To determine whether microscopically visible double-minute chromosomes (DMs) are derived from submicroscopic precursors, we monitored the amplification of the dihydrofolate reductase (DHFR) gene in 10 independent isolates of methotrexate (MTX)-resistant mouse cells. At every other doubling in MTX concentration, the cells were examined both microscopically, to detect the presence of microscopica...

Computer vision deals with image understanding at various levels. At the low level, it addresses issues such us planar shape recognition and analysis. Some classical results on differential invariants associated to planar curves are relevant to planar object recognition under different views and partial occlusion, and recent results concerning the evolution of planar shapes under curvature cont...

Amphiphilic block copolymers poly(LysAA-b-DMS) consisting of a hydrophilic poly(N-α-acrylamide-L-lysine) [poly(LysAA)] segment with different molecular weights and a hydrophobic polydimethylsiloxane (PDMS) segment were prepared as follows. The precursor copolymer poly(Boc-LysAA-OtBu-b-PDMS) was obtained from radical polymerization of N-α-acrylamide-N-ε-tert-butoxycarbonyl-L-lysine-tert-butylest...

The research product ...............................................................................................................................1
 Deformable mirrors: current state-of-the-art...........................................................................................2
 AO and MEMS DMs: relevance to astronomy and space science......................................................

1 The research of the first author was partially supported by NSF Grant DMS-9531675. The second author was partially supported by a Columbia University Faculty Research grant and NSF Grant DMS-9627870. The third author was partially supported by NSF Grant DMS-9704535. We thank Eric Conrad for some assistance with programming, and Peter Woit for excellent computing support. We thank David Ginzbu...

We prove a robust extension of the quantum adiabatic theorem. The theorem applies to systems that have resonances instead of bound states, and to systems for which just an approximation to a bound state is known. To demonstrate the theorem’s usefulness in a concrete situation, we apply it to shape resonances. Partially Supported by National Science Foundation Grant DMS–0907165. Partially Suppor...

Background: The Dynamic Modified Stochastic p-Median Problem (DMS-p-MP) is an important problem in supply chain network design, as it deals with the optimal location of facilities and allocation demand a dynamic uncertain environment. Methods: In this research paper, we propose mixed-integer linear formulation for DMS-p-MP, which captures key features allows efficient solution methods. DMS-p-MP...

Ocean-derived dimethyl sulfide (DMS) is widely concerning because of its hypothesized influence on global climate change. This study aims to explore the distribution characteristics and influencing factors DMS partial pressure carbon dioxide ( p CO 2 ) in Northwest Pacific Ocean, as well potential relationship between . A high-resolution, underway, shipboard measurement device was used determin...