A new Schiff base ligand, 2,2'-{pyridine-2,6-diylbis[nitrilo(E)methylylidene]}bis(4 bromophenol),has been synthesized by reaction of the 2,6-diamino pyridine with 5-bromo salicylaldehyde at ethanolunder refluxing. The structure of the synthesized compound resulted from the IR, 1HNMR, MS andUV spectroscopy and elemental analysis data. Formation Constant (kf) value of it’s complexes withCu2+, Ni2...

Several substituted-benzimidazole 3-(4-{5-Amino-6-fluoro-1-[2'-(1H-tetrazole-5-yl)-biphenyl-4ylmethyl]-1H-benzoimidazol-2-yl}-phenyl) -2-(substituted)thiazolidin-4-one were synthesized by condensation of various steps with various substituted aryl aldehydes reaction. Elemental analysis, IR, 1HNMR and mass spectral data confirmed the structure of the newly synthesized compounds. Synthesized and ...

The rapid and continuous progress in trace analysis of metals is associated with development of several new techniques such as spectrophotometry. Thiosemicarbazones have been used as chromogenic reagents in spectrophotometric determination of metals. In this study the synthesis and characterization of pyridoxal thiosemicarbazone (PDT) and 2-acetyl pyridine thiosemicarbazone (2-APT) using IR, MS...

A series of novel 3, 4-methylenedioxybenzene scaffold incorporated 1,3,5-trisubstituted-2-pyrazoline derivatives was synthesised as potent antitubercular agents via chalcone intermediates by reaction with hydrazines. The structures of the compounds were confirmed by IR, 1HNMR, 13CNMR and mass spectral data. The novel pyrazolines were screened for in vitro antitubercular activity by almar blue d...

Trimethoprim (TMP) is a dihydrofolate reductase (DHFR) inhibitor which prevents the conversion of dihydrofolic acid into tetrahydrofolic acid, resulting in the depletion of the latter and leading to bacterial death. Oral bioavailability of TMP is hindered by both its low solubility and low permeability. This study aims to prepare novel salts of TMP using anionic amino acids; aspartic and glutam...

Two new flavonoids, takakin 7-O-glucoside (1) and (2) bucegin 7-O-glucoside, and six other known compounds (3-8), takakin, isosctullarien, its 7-O-glucoside, takakin 8-O-glucoside, xanthotoxin and esculetin, were separated and identified from Glossostemon bruguieri. The new compounds were characterized using modern spectroscopic techniques, including UV spectroscopy, proton nuclear resonance (1...

Qin C., Li Y., Niu W., Ding Y., Zhang R., Shang X. (2010): Analysis and characterisation of anthocyanins in mulberry fruit. Czech J. Food Sci., 28: 117–126. The fruit of mulberry (Morus alba L., Moraceae) has been used as medicinal food in China for a long history. The pigment from the fruit extract is a kind of natural colourant for food processing and has potential medical and commercial valu...

A novel method of fabricating water-soluble bio-probes with ultra-small size such as NaYF4:Yb,Er (18 nm), NaGdF4:Yb,Er (8 nm), CaF2:Yb,Er (10 nm), PbS (7 nm), and ZnS (12 nm) has been developed to provide for the solubility switch of nanoparticles from oil-soluble to water-soluble in terms of hydrion rivalry aided by ultrasonic. Using NaYF4:Yb,Er (18 nm) as an example, we evaluate the propertie...