Aflatoxin B1 (AFB1), among other aflatoxins of the aflatoxin family, is the most carcinogenic and hazardous mycotoxin to animals and human beings with very high potency leading to aflatoxicosis. Selenium is an essential trace mineral possessing powerful antioxidant functions. Selenium is widely reported as an effective antioxidant against aflatoxicosis. By preventing oxidative liver damage, sup...

Two experiments were performed to screen bacilli isolated from quails for their aflatoxin removal potential and to assess the efficiency of their amelioration of experimental aflatoxicosis. Nonhemolytic bacilli were selected for in vitro aflatoxin B1 (AFB1) removal and conventional probiotic tests. The isolate with the highest scores was selected for assessment in field experiments and was iden...

Aflatoxin B1 (AFB1), the most common mycotoxin in human food and animal feed, produces hepatotoxic, genotoxic and immunosuppressive effects in multiple species. Selenium (Se) has emerged as an important element in the dietary prevention of various toxic agents. The present study was designed to scrutinize the protective effects of sodium selenite on the histological lesions and suppression of m...

The objective of this study was to investigate the protective effect of dietary natural sorbent-sodium humate (HuNa) on the prevention of aflatoxin B1 (AFB1) toxicity in the broiler chicken. Seventy-two (72) broiler hybrid Hybro birds were randomly divided into 4 groups: control group (G1) and 3 experimental groups (G2-G4) with addition of HuNa (G2); only AFB1 (G3) and HuNa; and AFB1 (G4). HuNa...

BACKGROUND A degradation study of aflatoxin B1 (AFB1) was carried out using a combination of physical and chemical methods. AFB1 was heated at 80 °C in the presence of acetic, citric and lactic acids for various time periods. The cytotoxicity of the degraded AFB1 and its products were determined by MTT assay. RESULTS The results showed that among the three organic acids lactic acid was most e...

effect of protexin to diminish negative consequences of feeding aflatoxin b1 (afb1) contaminated diet on performance, immune response, meat quality and ileal microbial flora were examined using 320 seven-day-old japanese quails fed four treatments [control diet (without additives), diet containing 2.5 mg afb1/kg, diet containing 150 mg protexin/kg, diet containing 2.5 mg afb1/kg+150 mg protexin...

Aflatoxin B1 (AFB1) is a potent dietary hepatocarcinogen in animals and probably in humans. Mutations (and altered expression) of the tumor suppresser gene p53 have been observed in liver tumors from patients exposed to high dietary AFB1. Inhalation of AFB1-laden grain dusts has been associated with an increased incidence of lung cancer in humans as well. We examined the effects of low concentr...

Background & Aims of the Study: Among aflatoxins, aflatoxin B1 (AFB1) is more toxic and dangerous. The presence AFB1 in poultry feed one most critical health economic problems industry. concern caused by contamination industry transfer toxins from to its products, such as meat, eggs, edible parts. Thus, developing scientific strategies for controlling nutrition protecting public very important....

Two experiments were performed to screen bacilli isolated from quails for their aflatoxin removal potential and to assess the efficiency of their amelioration of experimental aflatoxicosis. Nonhemolytic bacilli were selected for in vitro aflatoxin B1 (AFB1) removal and conventional probiotic tests. The isolate with the highest scores was selected for assessment in field experiments and was iden...

background: aflatoxin b1 (afb1) is a toxic metaboliteproduced by aspergillus species that contaminates a wide range ofagricultural products. objectives: this study was designed todevelop a rapid and highly sensitive immunoassay method inmicroarray format for quantitative detection of afb1 to evaluatethe potential of microarray platform for high-throughput screening,which can be beneficial in fo...