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Troponin senses Ca2+ to regulate contraction in striated muscle. Structures of skeletal muscle troponin composed of TnC (the sensor), TnI (the regulator), and TnT (the link to the muscle thin filament) have been determined. The structure of troponin in the Ca(2+)-activated state features a nearly twofold symmetrical assembly of TnI and TnT subunits penetrated asymmetrically by the dumbbell-shap...
55th ASMS Conference – Indianapolis 2007 www.chemistry.wustl.edu/~msf/ Overview Purposes •Evaluate the resolving power and sensitivity achievable with a new compensated trap for FTMS as a function of m/z and develop a protocol for tuning this trap. Methods •Sample empirically the cyclotron frequency surface at various cyclotron radii and z-mode amplitude distributions. •Compare the mass resolvi...
Several characterizations of weak cotype 2 and weak Hilbert spaces are given in terms of basis constants and other structural invariants of Banach spaces. For finite-dimensional spaces, characterizations depending on subspaces of fixed proportional dimension are proved.
Gilvocarcin V(1), C27H28O9, m.p. 264 approximately 267 degrees C (dec.), and gilvocarcin M(2), C26H26O9, m.p. 245 approximately 248 degrees C (dec.), are new antitumor antibiotics produced by Streptomyces gilvotanareus. The structure of gilvocarcins has been determined by chemical degradation, nmr and mass spectra. They have a benzonaphtopyran-one system, to which the furanose moiety is linked ...
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