BACKGROUND Scoliosis is a common spinal deformity that occurs often during adolescence. Previous studies suggested that adolescent idiopathic scoliosis (AIS) patients can have various aspects of their lives being affected, due to disease presentation and/or treatment received. It is important to define a reliable instrument based on which the affected patients' health-related quality of life ca...

A spirostanic saponin was isolated from the ethanolic extract of the aerial parts of Solanum laxum Steud. The compound, named luciamin, was characterised by NMR spectroscopy, mass spectrometry and chemical methods, as (22R, 25S)-spirost-5-en-3 beta, 15 alpha-diol 3-O-|beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranosyl-( 1 --> 4)-[alpha-L-rhamnopyranosyl-( 1 --> 2)]-beta-D-galactopyranoside|....

Methods Fifteen patients with AIS, aged 10-18, with curves 10 – 45 degrees, braced or not, were randomized into Schroth, or standard care, groups. The six-month Schroth intervention consists of weekly one-hour long group exercise sessions, combined with a daily 45-minute long home program, consisting of 3-4 exercises prescribed using an algorithm. Compliance was monitored with a logbook. SRS-22...

Accumulating evidence indicates the association between changes in circulating sex steroid hormone levels and development of diabetic nephropathy. However, renal synthesis hormones during diabetes is essentially unknown. Male Wistar rats were injected with streptozotocin (STZ) or vehicle. After one week, no functional structural parameters related to kidney damage observed STZ group; however, a...

For positive rank r elliptic curves E(Q), we employ ideal class pairingsE(Q)×E−D(Q)→CL(−D), for quadratic twists E−D(Q) with a suitable “small y-height” rational point, to obtain explicit number lower bounds that improve on earlier work by the authors. E(a):y2=x3−a, r(a), this givesh(−D)≥110⋅|Etor(Q)|RQ(E)⋅πr(a)22r(a)Γ(r(a)2+1)⋅log⁡(D)r(a)2log⁡log⁡D, representing general improvement classical b...

background and aims:il-22 is an α-helical cytokine.il-22 binds to a heterodimeric cell surface receptor composed of il-10r2 and il-22r1subunits.il-22r is expressed on tissue cells and it is absent on immune cells.il-22 and il-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. the aim of this study was to investigat...

Interleukin (IL)-22 is a member of the IL-10 family. Its main targets are epithelial cells, not immune cells. We examined IL-22 signal transduction in oral squamous cell carcinoma (OSCC) cells. Immunohistochemical staining revealed that IL-22R was expressed more highly in OSCC compared to normal regions. An IL-22R signal was also observed in metas...