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Matrix metalloproteinases (MMPs) and their tissue inhibitors may play important roles in tissue remodelling processes of the uterus. This study identified MMP-26 (endometase/matrilysin-2) in the endometrium of pregnant rhesus monkeys (Macaca mulatta) and monitored the spatial and temporal expression of the transcript and protein in the uteri on days 12, 18 and 26 of pregnancy. The partial monke...

26-Hydroxylation of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol and other C27-steroids was demonstrated in cultured skin fibroblasts from healthy individuals. Activities in skin fibroblasts were approximately 5-10% of those previously found in human liver homogenates, and were inhibited by CO. The apparent Km was lowest for 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol (1.3 mumol/li...

Oxidation of side chain of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol was studied in a patient with cerebrotendinous xanthomatosis (CTX) and in control subjects, using various subcellular fractions of liver homogenate and a method based on isotope dilution-mass spectrometry. In the control, 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol was converted into 5 beta-cholestane-3 alpha,7 alp...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 7.9 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 4.4 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 9.4 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 7.9 20 to 24 years . . . . . . . . . . . . . . . . . . . . . . . ...