BACKGROUND Current manufacturing methods for recombinant human factor VIII (rFVIII) within mammalian cell cultures are inefficient, hampering the production of sufficient amounts for affordable, worldwide treatment of hemophilia A. However, rFVIII has been expressed at very high levels by the transgenic mammary glands of mice, rabbits, sheep, and pigs. Unfortunately, it is secreted into milk wi...

Last lecture, we discussed Janus, which uses system call interposition to achieve software sandboxing isolation. We talked about a few problems that Janus had, particularly race conditions that can potentially allow malicious code to break software isolation property. Since then, a few more sandboxing projects have been implemented to address such issues. Today, we are going to look at a few re...

The e.p.r. signals attributable to a cytochrome bd-type ubiquinol:O2 oxidoreductase (cytochrome b-558-b-595-d) were studied in a cytoplasmic membrane preparation of Escherichia coli that had been grown on glycerol with fumarate as respiratory-chain oxidant. Two major high-spin ferric haem signals were resolved on the basis of their potentiometric behaviour: a rhombic high-spin species (gx = 6.2...

This study examined the hypothesis that 5HT3 mechanisms mediate the postprandial gastrocolonic response in humans. Fasting and postprandial colonic tone and motility were studied in 12 healthy volunteers and the effects of a selective 5HT3 antagonist, ondansetron assessed in a double blind, randomised, placebo controlled fashion. A manometry barostat assembly was positioned in the transverse or...

0747-5632/$ see front matter 2012 Elsevier Ltd. A doi:10.1016/j.chb.2011.12.015 ⇑ Corresponding author. Address: Human Resource Education Policy, Organization, and Leadership, Uni Champaign, 351 Education Building, 1310 S. 6th Stree Tel.: +1 217 333 0807; fax: +1 217 244 5631. E-mail addresses: [email protected] (S.J. Yoo), ha [email protected] (W. Huang). Acceptance of e-learning by employ...

Materials Research Center for Element Stra Nagatsuta, Midori-ku, Yokohama 226-8503, Laboratory for Materials and Structures Nagatsuta, Midori-ku, Yokohama 226-8503, ACCEL, Japan Science and Technology Age 332-0012, Japan Frontier Research Center, Tokyo Institute o Yokohama 226-8503, Japan † Electronic supplementary information kinetic analyses, catalytic performance, calculations. See DOI: 10.1...