in this study,oil was extracted from the liver and visceral fat of patin (pangasianodon hypophthalmus) and refined. the yield of oil after refining was 49.98%. the major yield loss (34.20%) happened during the degumming procedure. fatty acids found in the crude and refined oil were c12:0, c14:0, c14:1, c16:0, c16:1, c18:0, c18:1, c18:2, c18:3, c18:4, c20:0, c20:1, c20:4, c20:5, and c22:6. the d...

Arachidonic acid and other long-chain polyunsaturated fatty acids (PUFAs) are important structural components of membranes and are implicated in diverse signaling pathways. The Delta6 desaturation of linoleic and linolenic acids is the rate-limiting step in the synthesis of these molecules. C. elegans fat-3 mutants lack Delta6 desaturase activity and fail to produce C20 PUFAs. We examined these...

The objective of this study was to determine if children with phenylketonuria (PKU) have lower fatty acid concentrations in total erythrocyte lipid due to the phenylalanine restricted diet therapy compared to healthy control subjects. Dietary intake and fatty acid concentrations in total erythrocyte lipid were measured in twenty-one subjects (</=6 years of age) with PKU and twenty-three control...

The fatty acid composition of liver mitochondrial phospholipids from rats rendered deficient in essential unsaturated fatty acids has been determined, and compared with that of rats fed a diet containing corn oil. In addition to marked reductions in the amounts of linoleic and arachidonic acids esterified a t the &position of ethanolamine-, inositol-, and choline glycerophosphatides, the defici...

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All fats, including saturated fatty acids, have important roles in the body. However, the most important fats are those that the body cannot make and thus must come from the food we eat. These essential fatty acids (EFAs) are based on linoleic acid (omega-6 group) and alpha-linolenic acid (omega-3 group). We need both groups of essential fatty acids to survive. For various reasons EFA deficienc...

an 8-week feeding experiment was carried out on beluga (huso huso) juvenile to evaluate the effects of different levels of fish oil containing n-3 highly unsaturated fatty acids (n-3 hufas) on fish growth and fatty acid composition. the requirements of beluga juvenile for n-3 hufas were studied by feeding fish diets containing six different levels of n-3 hufas ranging from 1.56 to 17.25% (% of ...

PURPOSE Blue-light photooxidative damage has been implicated in the etiology of age-related macular degeneration (AMD). The macular pigment xanthophylls lutein (L) and zeaxanthin (Z) and n-3 fatty acids may reduce this damage and lower the risk of AMD. This study investigated the effects of the lifelong absence of xanthophylls followed by L or Z supplementation, combined with the effects of n-3...

The allegedly beneficial effect of biotin in the treatment of infantile 'flexural' seborrhoeic dermatitis was evaluated in a double-blind controlled study. No beneficial effect could be confirmed, and it is therefore unlikely that this disease is caused by biotin deficiency. Nor could this scaly dermatitis be ascribed to an essential fatty acid deficiency. Serum and adipose tissue fatty acids r...

Results We diagnosed 148 cases of IEM by urine GC-MS analysis, including 97 cases of organic acid disorders, 41 cases of amion acid disorders and 10 cases of fatty acid oxidative disorders. Methylmalonic aciduria (MMA) was most common (48 cases), followed by urea cycle disorder (21 cases), phenylketonuria (20 cases), propionic aciduria (11 cases), multiple carboxylase deficiency (8 cases), glut...