Aims The purpose of this study was to validate ST segment resolution as a non-invasive marker for patency of the infarct-related artery 90 min after the start of streptokinase therapy in patients with acute myocardial infarction. Methods and Results In the HIT-4 angiographic substudy, 447 patients with acute myocardial infarction </=6 h received 1.5 million IU streptokinase. Angiograms of the i...

background: s. alopecuroides, z. officinale and m. officinalis are used traditionally in the treatment of pain. objective: to evaluate the plants effects in the rat formalin test and their activity on the opioid receptors. methods: each rat was placed individually in a cage for 30 min to get acclimated. then 0.05 ml of 10% formalin was injected subcutaneously into the dorsal surface of the righ...

occlusion. Thus, from a mechanistic perspective, achieving early vessel patency limits the extent of myocardial injury. The term ‘door-to-balloon (DTB) time’, defined as the time from first medical contact to the time of first coronary device deployment, has become a mantra of STEMI management. First medical contact, often poorly characterized in the field, is usually defined by time of hospita...

OBJECTIVES This study was designed to determine the relationship between clopidogrel and early ST-segment resolution (STRes) and the interaction of the two with clinical outcomes after fibrinolysis. BACKGROUND ST-segment resolution is an early noninvasive marker of coronary reperfusion. METHODS The CLARITY-TIMI 28 (Clopidogrel as Adjunctive Reperfusion Therapy-Thrombolysis in Myocardial Inf...

Regulation of maximal Na(+)-K(+)-ATPase activity in vastus lateralis muscle was investigated in response to prolonged exercise with (G) and without (NG) oral glucose supplements. Fifteen untrained volunteers (14 males and 1 female) with a peak aerobic power (Vo(2)(peak)) of 44.8 +/- 1.9 ml.kg(-1).min(-1); mean +/- SE cycled at approximately 57% Vo(2)(peak) to fatigue during both NG (artificial ...

BACKGROUND Arterial blood gases (ABGs) are often sampled incorrectly, leading to a 'mixed' or venous sample. Delays in analysis and air contamination are common. OBJECTIVES We measured the effects of these errors in patients with chronic obstructive pulmonary disease (COPD) exacerbations and controls. METHODS Arterial and venous samples were analyzed from 30 patients with COPD exacerbation ...

Introduction: Blood loss is a common concern during functional endoscopic sinus surgery (FESS). The present study aimed to evaluate the efficacy of dexmedetomidine (DEX) in intraoperative bleeding and surgical field in FESS.   Materials and Methods: This double-blind randomized clinical trial was conducted on 72 patients within the age range of 16-60 years who underwent ...

Background: S. alopecuroides, Z. officinale and M. officinalis are used traditionally in the treatment of pain. Objective: To evaluate the plants effects in the rat formalin test and their activity on the opioid receptors. Methods: Each rat was placed individually in a cage for 30 min to get acclimated. Then 0.05 mL of 10% formalin was injected subcutaneously into the dorsal surface of the r...

laboratory experiments were performed to determine the effect of various scarification treatments at four temperature regimes on germination of licorice seeds . a randomized complete block design with four replications was used. germination counts were made every day for 2 weeks. at 50c, none of the chemically and mechanically scarified and non scarified seeds germinated. at 15, 25, and 350...