Severe malaria claims 1.5 to 2.7 million lives annually most of which are young children in rural areas in sub-Saharan Africa. We retrospectively reviewed the files of 387 patients, admitted and treated for severe malaria according to WHO guidelines, in the Bertoua provincial hospital, a peripheral health center in East Cameroon from 1st October 1998 to 30h October 2000. Our main objective was ...

We report the δ34S and δO(SO4) measured in gypsum, pyrite, and elemental sulfur through a 456-m thick sediment core from the center of the Dead Sea, representing the last ∼200 kyrs, as well as from the exposed glacial outcrops of the Masada M1 section located on the margins of the modern Dead Sea. The results are used to explore and quantify the evolution of sulfur microbial metabolism in the D...

OBJECTIVE The aim of this study was to assess clinical features and colonic transit patterns in Brazilian children with refractory constipation. METHODS From 2010 to 2013, 79 constipated patients received follow-up care in a tertiary hospital. Of these patients, 28 (aged 8-14 years) were refractory to conventional therapy and underwent a simplified visual method of nuclear colonic transit stu...

We present the Chandra study of the intermediately distant (z = 0.194) cluster of galaxies MS 0839.9+2938. By performing both the projected and deprojected spectral analyses, we find that the gas temperature is approximately constant at about 4 keV in 130 − 444h 70 kpc. In the inner regions, the gas temperature descends towards the center, reaching < ∼ 3 keV in the central 37h 70 kpc. This infe...

BACKGROUND Multidrug resistance (MDR) directly contributes to the clinical failure of chemotherapy in breast cancer (BCA). β-elemene is a natural antitumor drug from plants. We previously confirmed that MDR could be reversed by β-elemene. In this study, we intended to investigate the reversal effect of β-elemene on MDR in human BCA adriacin (Adr) -resistant MCF-7 cells (MCF-7/Adr) and docetaxel...

Millimeter continuum and spectral line observations with 10", 30", and 60" resolution are used to characterize the structure and chemistry of the gas around the young, embedded star, IRAS 05338-0624. On arcminute scales, emission from dense gas tracers outline an isolated condensation centered on the IRAS source position. The condensation is characterized by a size of ~60", a density of 2 x 105...

The effectiveness of intra-articular (IA) morphine in arthroscopic procedures of the knee joint was analysed in all randomised and controlled trials that included injections of morphine and placebo into the knee joint, and where the data were analysable. Sensitivity of the studies and effectiveness were analysed for three different periods: immediate (0-2h), early (2-6h) and late (6-30h). Sensi...

We use very large cosmological N–body simulations to obtain accurate predictions for the two-point correlations and power spectra of mass-limited samples of galaxy clusters. We consider two currently popular cold dark matter (CDM) cosmogonies, a critical density model (τCDM) and a flat low density model with a cosmological constant (ΛCDM). Our simulations each use 10 particles to follow the mas...

OBJECTIVE To characterize the workforce in the pharmaceutical services in the primary care of the Brazilian Unified Health System (SUS). METHODS This is a cross-sectional and quantitative study, with data from the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços, 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicin...

from earlier experiments. Similar results were obtained for the freshwater bivalve Anodonta cygnea (Gade et al., 1975). In this animal, acetate and propionate were responsible for over 75 % of total accumulated end products after 30h of anaerobiosis. As volatile fatty acids can be stored in the animal in esterified form, some of the homogenates obtained in the experiments represented in Table 1...