In this paper, natural frequencies of the sandwich plates with soft flexible core and composite face sheets are obtained. Three-Dimensional (3D) finite element method (FEM) is used for constructing and analyzing of the sandwich plates to obtain their natural frequencies. Continuity conditions for transverse shear stresses at the interfaces as well as transverse flexibility and transverse normal...

Three-dimensional (3D) printing has evolved massively during the last years and is demonstrating its potential in tissue engineering, wound dressings, cell culture models for drug testing, prosthesis, to name a few [...]

OBJECTIVE Experimental wounding of articular cartilage results in cell death at the lesion edge. The objective of this study was to investigate whether inhibition of this cell death results in enhanced integrative cartilage repair. METHODS Bovine articular cartilage discs (6 mm) were incubated in media containing inhibitors of necrosis (Necrostatin-1, Nec-1) or apoptosis (Z-VAD-FMK, ZVF) befo...

Effective exudate retention by dressings requires close and intimate dressing-wound contact, immediately continuously after the dressing application. Any spaces may allow for build-up of non-retained fluids, causing pooling which forms a favourable environment pathogen growth. Maceration follow if pooled exudates spread to peri-wound skin. Dressings with claimed 3D-shape-conformation technology...

abstract: the present study deals with the buckling analysis of the laminated composite truncated conical sandwich shells with flexible core subjected to combined axial compressive load and external pressure. higher order governing equations of the motion are presented for conical composite sandwich shells, where they are derived from the hamilton principle. then, by the use of improved higher-...

Cutaneous wound repair regenerates skin integrity, but a chronic failure to heal results in compromised tissue function and increased morbidity. To address this, we have used an integrated approach, using nanobiotechnology to augment the rate of wound reepithelialization by combining self-assembling peptide (SAP) nanofiber scaffold and Epidermal Growth Factor (EGF). This SAP bioscaffold was tes...

A pencil core with an intact pencil tip was excised from the thigh of a 60-year-old male 53 years after a puncture wound. Histologic examination of the excised pencil core and the surrounding tissue revealed a foreign body reaction with abundant entrapped dark black pigment and chronic reparative changes, including dense sclerosis and focal granulation tissue formation.

BACKGROUND Scar heterogeneity identified with contrast-enhanced cardiac magnetic resonance (CE-CMR) has been related to its arrhythmogenic potential by using different algorithms. The purpose of the study was to identify the algorithm that best fits with the electroanatomic voltage maps (EAM) to guide ventricular tachycardia (VT) ablation. METHODS AND RESULTS Three-dimensional scar reconstruc...

The combination of a chitosan 3D-printed scaffold with hydrogel matrix containing an elastin-like polypeptide functionalized the epidermal growth factor (HEGF) was evaluated as possible strategy to obtain bioactive platform stimuli-responsive properties. We designed chitosan/HEGF hybrid and examined physico-chemical properties in vitro behavior when contact simulated biological fluids. Primary ...