نتایج جستجو برای: 497

تعداد نتایج: 2679  

2017
Henghui Cheng Jin Xue Shouhua Yang Yaobin Chen Yu Wang Yuanli Zhu Xiaoyan Wang Dong Kuang Qiurong Ruan Yaqi Duan Guoping Wang

Persistent activation of IGF1R/mTOR signaling pathway plays crucial role in the development of hepatocellular carcinoma (HCC). Therefore, our goal was to elucidate microRNAs (miRNAs) targeting IGF1R/mTOR and the therapeutic potential of single or dual miRNA on HCC development. In this study, we found that miR-497 and miR-99a that target the 3'-UTR of both IGF1R and mTOR were down-regulated in H...

2002
Sariel Har-Peled

“Shortly after the celebration of the four thousandth anniversary of the opening of space, Angary J. Gustible discovered Gustible’s planet. The discovery turned out to be a tragic mistake. Gustible’s planet was inhabited by highly intelligent life forms. They had moderate telepathic powers. They immediately mind-read Angary J. Gustible’s entire mind and life history, and embarrassed him very de...

2016
Qianshan Ding Ke He Tao Luo Yunchao Deng Hanning Wang Hao Liu Jinqian Zhang Kaiyun Chen Jinfeng Xiao Xiaopeng Duan Rui Huang Zhenglin Xia Wenjie Zhou Jinliang He Honggang Yu Xingyuan Jiao Guoan Xiang

The aim of this study is to clarify the clinical implication and functional role of structure specific recognition protein 1 (SSRP1) in hepatocellular carcinoma (HCC) and explore the underlying mechanism of aberrant high expression of SSRP1 in cancers. In the present investigation, we validated that SSRP1 was upregulated in HCC samples. We also demonstrated that its upregulation was associated ...

2011
Dan Li Yulan Zhao Changxing Liu Xiaona Chen Yanting Qi Yue Jiang Chao Zou Xiaolong Zhang Shunying Liu Xuejing Wang Dan Zhao Qiang Sun Zhenbing Zeng Andreas Dress Marie C. Lin Hsiang-Fu Kung Hallgeir Rui Ling-Zhi Liu Feng Mao Bing-Hua Jiang Lihui Lai

Purpose: To investigate expression, regulation, potential role and targets of miR-195 and miR-497 in

Journal: :Proceedings of Anticancer Research 2022

Objective: To investigate the effect of small nucleolar host gene 12 (SNHG12) on migration and invasion human lung cancer cells by regulating angiostatin binding protein through microribonucleic acid (microRNA)-497. Methods: A549, H1299, PC9 were cultured in Roswell Park Memorial Institute (RPMI)-1640 medium containing 10% fetal bovine serum, bronchial epithelial (HBE) Dulbecco’s modified eagle...

2015
Katharina Troppan Kerstin Wenzl Martin Pichler Beata Pursche Daniela Schwarzenbacher Julia Feichtinger Gerhard G. Thallinger Christine Beham-Schmid Peter Neumeister Alexander Deutsch William Chi-shing Cho

Micro-RNAs (miRNAs) are short non-coding single-stranded RNA molecules regulating gene expression at the post-transcriptional level. miRNAs are involved in cell development, differentiation, apoptosis, and proliferation. miRNAs can either function as tumor suppressor genes or oncogenes in various important pathways. The expression of specific miRNAs has been identified to correlate with tumor p...

Journal: :OECD guidelines for the testing of chemicals 2023

2002
Guy Salama

Milou-Daniel Drici, Linda Baker, Patricia Plan, Jacques Barhanin, Georges Romey and Guy Mice Display Sex Differences in Halothane-Induced Polymorphic Ventricular Tachycardia Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: ...

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