نتایج جستجو برای: 5 and 5
تعداد نتایج: 17026982 فیلتر نتایج به سال:
5-Methylcytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian cells by the ten-eleven translocation (Tet) family of dioxygenases. While 5mC has been extensively studied, we have just started to understand the distribution and function of 5hmC in mammalian genomes. Despite the fact that this new epigenetic mark has only been discovered three years ago, exciting progress ...
5-Hydroxymethylcytosine (hmC) was recently detected as the sixth base in mammalian tissue at so far controversial levels. The function of the modified base is currently unknown, but it is certain that the base is generated from 5-methylcytosine (mC). This fuels the hypothesis that it represents an intermediate of an active demethylation process, which could involve further oxidation of the hydr...
A new method based on an autoregressive noise model of order 1 is introduced to the problem of detecting the number of components in fMRI data. Unlike current information-theoretic criteria like AIC, MDL, and related PPCA, which do not incorporate autocorrelations in the noise, the new method leads to more consistent estimates of the model order, as illustrated in simulated and real fMRI restin...
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