M A T E R I A L S AND M E T H O D S The growth-inhibitory effects of ketoconazole, an antifungal agent which inhibits arachid0nic acid iip0xygenases and cyt0chr0me P-450 enzymes, were tested in human colon and breast cancer cell lines. In the serum independent HT29-S-B6 colon cell clone, ketoconazole reduced cell proliferation and [3H]thymidine incorporation in a dose-dependent fashion, with a ...

M A T E R I A L S AND M E T H O D S The growth-inhibitory effects of ketoconazole, an antifungal agent which inhibits arachid0nic acid iip0xygenases and cyt0chr0me P-450 enzymes, were tested in human colon and breast cancer cell lines. In the serum independent HT29-S-B6 colon cell clone, ketoconazole reduced cell proliferation and [3H]thymidine incorporation in a dose-dependent fashion, with a ...

Aminooxyacetate, a known inhibitor of transaminase reactions and glycine decarboxylase, promotes rapid depletion of the free pools of serine and aspartate in nitrate grown Lemna minor L. This compound markedly inhibits the methionine sulfoximine-induced accumulation of free ammonium ions and greatly restricts the methionine sulfoximine-induced depletion of amino acids such as glutamate, alanine...

Bottlebrush polymer thin films may be attractive for the preparation of antifouling and/or stimuli-responsive surface coatings due to the high grafting density and conformational flexibility of polymeric side chains, but bottlebrush polymer thin films have not been previously reported and their surface properties are unknown. Herein, we report a study of the surface properties of mixed bottlebr...