نتایج جستجو برای: 6a
تعداد نتایج: 3042 فیلتر نتایج به سال:
The Quellung reaction has long been the standard method for pneumococcal serotyping (7); however, the new serotype 6C is reportedly indistinguishable from serotype 6A using this method (8). We report an anomalous Quellung reaction associated with serotype 6C, which may aid in diagnostic interpretation. The 7-valent pneumococcal conjugate vaccine was introduced in Australia for indigenous and ot...
BACKGROUND Matrix metalloproteinases, such as stromelysin-1, are implicated in the pathogenesis of coronary artery disease (CAD) and acute myocardial infarction (MI). A 5A/6A promoter polymorphism can regulate the transcription of the stromelysin-1 gene in an allele-specific manner. Evidence has been presented that the 6A allele is associated with the progression of coronary heart disease (CHD)...
Multiple sclerosis (MS) is a progressive autoimmune disease of the central nervous system (CNS) in which demyelination, axonal inflammation and damage occurs. The aim of present study was to investigate the influence of matrix metalloproteinase (MMP)-3 5A/6A and its interaction with MMP-7 A-181G polymorphism on the risk and the clinical course of MS. We studied 121 patients and 106 healthy indi...
BACKGROUND Epidemiological studies have investigated the association between matrix metalloproteinase-3(MMP-3) gene-1171 5A/6A polymorphism and rheumatoid arthritis (RA), but the results were inconsistent. To evaluate the specific relationship, we performed a meta-analysis to clarify the controversies. METHODS The relevant literatures dated to December 07th 2013 were retrieved from PubMed, EM...
BACKGROUND AND OBJECTIVES Hypertension develops as a result of cardiac hypertrophy and fibrosis or as a result of exchange of the extracellular matrix. In particular, matrix metalloproteinase (MMP)-3 is a major enzyme involved in the reconstruction of the arterial intima through activation of other MMPs. We analyzed MMP-3 genotypes in hypertensive and normotensive adolescents and sought to dete...
Streptococcus pneumoniae clinical isolates were recently described that produced capsular polysaccharide with properties of both serotypes 6A and 6B. Their hybrid serological property correlated with mutations affecting the glycosyltransferase WciP, which links rhamnose to ribitol by an α(1-3) linkage for serotypes 6A and 6C and an α(1-4) linkage for serotypes 6B and 6D. The isolates had mutati...
A panel of 13 monoclonal antibodies to avian lipoprotein lipase (LPL) was screened for inhibition of LPL binding to primary avian adipocytes. One monoclonal antibody, designated xCAL (monoclonal antibody to chicken adipose lipoprotein lipase) 3-6a, was found to inhibit the binding of LPL to primary avian adipocytes. In solid phase assays, xCAL 3-6a inhibited the binding of LPL to both heparan s...
PURPOSE Recently a common variant of the TGFBR1 gene, TGFBR1*6A, has been proposed to act as a low-penetrance tumor susceptibility allele for colorectal cancer, but data from published studies with individually low statistical power are conflicting. To further evaluate the relationship between TGFBR1*6A and colorectal cancer risk, we have conducted a large case-control study and a meta-analysis...
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