BACKGROUND There is debate about the psychometric characteristics of the three-level EuroQol five-dimensional questionnaire (EQ-5D-3L) for use in epilepsy. In response to the concerns, an epilepsy-specific preference-based measure (NEWQOL-6D) was developed. The psychometric characteristics of the NEWQOL-6D, however, have not been assessed. OBJECTIVES To investigate the validity and responsive...

OBJECTIVES/HYPOTHESIS To evaluate the changes in health-related quality of life in unilateral adult cochlear implant patients using the Medical Outcome Study Short-Form Survey-36 (SF-36) and the Health Utility Index Mark 3 (HUI-3). To do so, a health utility index was obtained by converting the SF-36 to the Medical Outcome Study Short-Form Survey-6D (SF-6D) to permit comparison with HUI-3 score...

Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that directs many of the cellular responses to hypoxia. In these studies, we have used a mouse model containing a cardiac-specific, oxygen-stabilized, doxycycline (Dox)-off regulated HIF-1α transgene to probe the role of HIF-1α in cardioprotection. Hearts used in these studies were derived from wild-type (WT), noninduced (Non-I), an...

We develop a systematic framework for realizing general anomaly-free chiral 6D supergravity theories in F-theory. We focus on 6D (1, 0) models with one tensor multiplet whose gauge group is a product of simple factors (modulo a finite abelian group) with matter in arbitrary representations. Such theories can be decomposed into blocks associated with the simple factors in the gauge group; each b...

OBJECTIVES SF-6D is a preference-based measure of health developed to estimate utility values from the SF-36. The aim of this study was to estimate a weighting system for the SF-6D health states representing the preferences of a sample of the Southern Brazilian general population. METHODS A sample of 248 health states defined by the SF-6D was valued by a sample of the southern Brazilian popul...

This paper proposes a new memristor model and uses pinched hysteresis loops (PHL) to prove the characteristics of model. Then, 6D fractional-order memristive Hopfield neural network (6D-FMHNN) is presented by using this simulate induced current, bifurcation coexistence attractor fractional studied. Because 6D-FMHNN has chaotic characteristics, we also use generate random number apply it field i...

bacterial resistance is a major drawback in chemotherapy of infectious diseases. in this investigation a new series of 3,5-diarylamide dihydropyridines containing 2-benzylsulfonylimidazol at 4 position have been synthesized and studied for their enhancing effect on the antibacterial activities of different penicillins against a resistant clinical isolate of s. aureus using disc diffusion method...

BACKGROUND Multi-attribute utility measures are preference-based health-related quality of life measures that have been developed to inform economic evaluations of health care interventions. The objective of this study was to compare the empirical validity of two multi-attribute utility measures (EQ-5D and SF-6D) based on hypothetical preferences in a large maternity population in England. ME...

introduction: escherichia coli is one of the important pathogens in human with global importance. because of the necessity for identification and the use of novel antibacterial compounds against e. coli , in this present study we focused on the antibacterial effects of synthesized thiazole, imidazole and tetrahydropyridine derivatives on e. coli .   methods : for evaluation of antibacterial eff...

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