Background/Aims: Recently we have shown that NSC-631570 (Ukrain) is a safe and effective drug in the treatment of unresectable pancreatic cancer. The aim of this study was to determine the effectiveness of the combined treatment with Gemcitabine and NSC-631570 in the adjuvant treatment of resected advanced pancreatic cancer. Methodology: 30 patients received adjuvant chemotherapy following surg...

Oestrogens exert important effects on the reproductive as well as many other organ systems in both men and women. The history of the discovery of oestrogens, the mechanisms of their synthesis, and their therapeutic applications are very important components of the fabric of endocrinology. These aspects provide the rationale for highlighting several key components of this story. Two investigator...

At the Annual Meeting in New Orleans on June 21–24 2014, the Institute of Food Technologists (IFT) will be celebrating their 75th anniversary. Our journal is a bit older, with Food Research (the precursor to the Journal of Food Science) publishing its first issue in January of 1936. Science has made tremendous progress in the past 75 years. One case in point occurred 60 years ago with the publi...

This article takes both a short-term and a long-term look at trends in social welfare expenditures under public programs. For fiscal year 1975, inflation and the recession were the key to developments. Inflation ate up more than half the 20 percent ($47 billion increase--the largest in the history of the series--partly as the result of antirecession measures. After adjustment for population and...

Amino acids and peptides are known to bind metal ions, in some cases very strongly. There are only a few examples of exploiting this binding in sensors. The review covers the current literature on the interaction of peptides and metals and the electrochemistry of bound metal ions. Peptides may be covalently attached to surfaces. Of particular interest is the attachment to gold via sulfur linkag...