An efficient and greener protocol for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one using tetradecyltrimethylammonium bromide (TTAB) at room temperature in water is described.

This minireview describes the syntheses, structure-photophysical properties relationship, and bioimaging applications of fluorescent coumarins, xanthenes, BODIPYs, cyanines. Advantages disadvantages emissive units are also discussed, as general practical issues that need to be considered when using fluorophores in a biological setting.

The stereoselectivity and stereospecificity of the triflate-mediated intramolecular Schmidt reaction substituted 3-(1-azidocyclohexyl)propanol derivatives leading to octahydro-1H-pyrrolo[1,2-a]azepine, structural skeleton several important families alkaloids such as Stemona alkaloids, has been examined. involves an initial SN2 between azide moiety triflate affording intermediate spirocyclic ami...

2-Amino-1,3-dimethylimidazolium 2,2-dimethyl-4,6-dioxo-1,3-dioxanide (6) has been obtained from the reaction of 2,2-dimethyl-4,6-dioxo-1,3dioxan (1, “Meldrum’s acid”) and 2-imino-1,3-dimethylimidazoline (5) in excellent yield. The unit cell of 6 contains two crystallographically independent anions lying on crystallographic mirror planes. The structure of the anion is compared with that of compo...

In order to determine the regularities of the structure-analgesic activity relationship, the peculiarities of obtaining, the spatial structure, and biological properties of 4-methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylic acid and some of its derivatives have been studied. Using nuclear magnetic resonance (NMR) spectroscopy and X-ray diffraction analysis, it has been proven that varying t...

The synthesis and pharmacological activity of some aminoalcoholic derivatives of 8-caffeinethioglycolic acid was studied. The structure of the synthesized compounds was proved by microanalysis, IRand H-NMR spectra. All of the investigated compounds were found to be practically non-toxic (LD50 p.o. > 5 g kg in mice) and less toxic compared to caffeine. The compounds were investigated for antihyp...

Several photosensitizing agents, which are activated by illumination with sunlight or artificial light sources, have been shown to be accumulated in significant amounts by a variety of insects when they are administered in association with suitable baits. The subsequent exposure of such insects to UV/visible light leads to a significant drop in survival. Of the photosensitizers tested so far, x...

A new, effective preparative method has been proposed and the synthesis of a series of N-(arylalkyl)-1-R-4-hydroxy-2,2-dioxo-1H-2λ(6),1-benzothiazine-3-car-boxamides has been carried out. It has been shown that amidation of alkyl 1-R-4-hydroxy-2,2-dioxo-1H-2λ(6),1-benzothiazine-3-carboxylates with arylalkyl-amines in boiling xylene proceeds with good yield and purity to the corresponding N-(ary...