Stromal Derived Factor 1 (SDF1 or CXCL12), is a chemokine known to be critical for the migration of cells in several tissue systems including the homing of the hematopoietic stem cell (HSC) to its niche in the bone marrow. A comparative analysis of miRNA expression profiles of two stromal cell lines, distinguishable by function and by CXCL12 expression (CXCL12+ and CXCL12-), revealed that the C...

Leukotrienes are reported to be potent proinflammatory mediators that play a role in the development of several inflammatory diseases such as asthma, rheumatoid arthritis and periodontal disease. Leukotrienes have also been associated with protection against infectious diseases. However, the role of leukotrienes in Mycobacterium tuberculosis infection is not understood. To answer this question,...

Familial renal glycosuria (FRG) is caused by mutations in the SLC5A2 gene, which codes for Na+-glucose co-transporters 2 (SGLT2). The aim of this study was to analyze and identify the mutations in 16 patients from 8 families with FRG. All coding regions, including intron-exon boundaries, were analyzed using PCR followed by direct sequence analysis. Six mutations in SLC5A2 gene were identified, ...

We developed a goal-driven methodology for eliciting and modeling the requirements of a business-toconsumer application. It has two phases: e-commerce strategy formulation and eliciting system requirements. In the first phase, an EC value matrix is used to develop a strategy and value-adding services for a business and then necessary customized requirements are identified. In the second phase, ...

Taşıyıcı, eşyanın taşınmak üzere teslim alınmasından edilmesine kadar geçecek süre içinde, zıyaından, hasarından veya teslimindeki gecikmeden doğan zararlardan sorumludur. Taşıma hukukunda, taşıyıcının tazminat sorumluluğu prensip olarak belirli bir tutar ile sınırlandırılmıştır. Ancak TTK m. 886’ya göre taşıyıcı; zarara, kasten pervasızca ve zararın meydana gelmesi ihtimalinin bilinciyle sebep...

In this paper, we establish a theorem of Bombieri–Vinogradov type for exponential sums over Piatetski-Shapiro primes p = [n1/γ] with 865/886 < γ 1.

BACKGROUND Acute renal failure (ARF) is an important clinical problem with a high mortality and morbidity. One of the primary causes of ARF is ischemia/reperfusion (I/R). Inflammatory process and oxidative stress are thought to be the major mechanisms causing I/R. MK-886 is a potent inhibitor of leukotrienes biosynthesis which may have anti-inflammatory and antioxidant effects through inhibitio...

By 3 Hsiu-Yun Shih 4 Yusen E. Lin* 5 Graduate Institute of Environmental Education, 6 National Kaohsiung Normal University, Kaohsiung, Taiwan 7 8 All corresponding should be addressed to 9 Yusen E. Lin, Ph.D., MBA 10 Graduate Institute of Environmental Education 11 National Kaohsiung Normal University 12 62 Shen-chong Rd, Yanchao 13 Kaohsiung, Taiwan 824 14 Work Telephone: +886-7-6051036; Fax: ...