The somatotropic axis, and particularly growth hormone-releasing hormone (GHRH), is implicated in the regulation of sleep-wake activity. To evaluate sleep in chronic somatotropic deficiency, sleep-wake activity was studied in dwarf (dw/dw) rats that are known to have a defective GHRH signaling mechanism in the pituitary and in normal Lewis rats, the parental strain of the dw/dw rats. In additio...

Leaf area (LA) is a valuable key for plant physiological studies, therefore accurate and simple models for LA determination are important for many experimental comparisons. A greenhouse experiment was conducted from October 2009 to February 2010 in two basil cultivars (Purple Ruffles and Genovese) to estimate LA, leaf dry weight (DW), leaf fresh weight (DW) and leaf dimensions (width-W and leng...

The extraction method is critical for the recovery of phenolic compounds. The main goal was to evaluate the effect of an extraction process from mango seed on their phenolic profile, antioxidant and antimicrobial capacities. Phenolic extraction was performed in different steps: maceration, alkaline hydrolysis, acid/alkaline hydrolysis, polar and non-polar fraction of an ethyl acetate separation...

CRISPR-Cas (clustered regularly interspaced short palindromic repeats—CRISPR associated proteins) is a RNA-guided defense immune system that prevents some genetic elements such as plasmids and virus from getting into the bacterial cells. Zymomonas mobilis is an ethanologenic bacterium, which encodes a subtype I-F CRISPR-Cas system containing three CRISPR loci and a far distant cas gene cluster....

objectives: to assess the effect of lactic acid (la) on microleakage of silorane-based composite restorations and methacrylate-based composites with self-etch and etch-and-rinse bonding systems. materials and methods: class v cavities were prepared in 120 extracted human teeth, divided into four groups and restored as follows: 1. silorane-based composite+p90 adhesive system (p90); 2. filtek z25...

BACKGROUND AND PURPOSE Diffusion-weighted (DW) imaging has limited spatial resolution, especially in the z direction. We decreased the section thickness of DW imaging to 3 mm to determine if this change improves the depiction of small infarcts and if it affects stroke diagnosis. METHODS We studied conventional (5-mm section thickness, 1-mm intersection gap) and thin-section (3-mm section thic...

Agomelatine is a new antidepressant that is a potent agonist of melatonin Abstract receptors and an antagonist of the serotonin 5-HT2C receptor subtype. It is in late-phase trials for the treatment of major depressive disorder (MDD). Symptoms of depression significantly improved with agomelatine compared with placebo in large placebo-controlled trials, and agomelatine appears to be as efficacio...

A data warehouse (DW) is a large centralized database that stores data integrated from multiple, usually heterogeneous external data sources (EDSs). DW content is processed by so called On-Line Analytical Processing applications, that analyze business trends, discover anomalies and hidden dependencies between data. These applications are part of decision support systems. EDSs constantly change ...