UNLABELLED Emotional and cognitive abnormalities are common in adult hypothyroidism. Few studies, however, have evaluated cerebral perfusion and metabolism in this disorder. The aims of this study were to compare regional cerebral blood flow (rCBF) between hypothyroid patients and healthy subjects and assess flow during the euthyroid state after treatment. METHODS Ten mildly hypothyroid patie...

BACKGROUND Hereditary Coproporphyria (HCP) is characterized by abdominal pain, neurologic symptoms and psychiatric disorders, even if it might remain asymptomatic. The pathophysiology of both neurologic and psychiatric symptoms is not fully understood. Therefore, aiming to evaluate a possible role of brain blood flow disorders, we have retrospectively investigated cerebral perfusion patterns in...

UNLABELLED The constant-volume urinary bladder model in the standard MIRD Pamphlet No. 5 (Revised) phantom has recognized limitations. Various investigators have developed detailed models incorporating more physiologically realistic features, such as expanding bladder contents and residual volume, and variable urinary input rate, initial volume and first void time. We have reviewed these publis...

background the ability to follow the distribution and migration of biologically active cells in human is essential for the development of cell-based therapies and diagnostics. nuclear medicine imaging is widely applied in clinic as an attractive technique for in vivo wbc and stem cell tracking. the aim of this study was to evaluate prosthesis infection of a 51 years old man with previous histor...

We have determined cerebral blood flow (CBF) and the single-pass cerebral extraction (E) of several putative agents for external imaging of CBF. Simultaneous measurements of blood flow and extraction were performed in 106 rats. For all agents, comparison of linear and exponential regressions of E on CBF indicates that this relationship can be described as linear over the range of flows studied....

UNLABELLED Our objective in this study was to evaluate whether measurement of quantitative uptake of (99m)Tc-methylene diphosphate (MDP) and (99m)Tc-hexamethylpropyleneamine oxime (HMPAO) white blood cells (WBCs) is useful in detecting osteomyelitis in peripheral bony lesions. METHODS Twenty-four patients (12 men and 12 women; age range, 25-72 y) were referred for imaging because of clinicall...

Technetium-d, HMPAO SPECT was performed in 70 patients suffering from intracerebral tumors of various histologic types (glioma n = 30, meningioma n = 19, metastases n = 10, angioma n = 3, neuroma n = 2, lymphoma n = 2, neurocytoma n = 1, epidermoid n = 1, gliosis n = 1, cholesteatoma n = 1). Tumor classification was histologically verified in all subjects except in two cases with inoperable ang...

A new method that employs a cerebral perfusion imaging agent, 99mTc-HMPAO, is described for identifying those patients who clinically pass an internal carotid artery balloon test occlusion but who then may develop a cerebral infarction after permanent occlusion. Test balloon occlusion of the internal carotid artery was performed in 17 patients, and 99mTc-HMPAO was injected intravenously while t...