T breastand ovarian-specific tumor suppressor protein, BRCA1, has been implicated in regulating the nuclear processes of repair of damaged DNA, chromatin remodeling, and transcription. Although many have sought specific DNA sequences bound by BRCA1, no such sequences have been reported. In new research described in this issue of PNAS (1), BRCA1 protein is shown to bind to DNA with high affinity...

new study identifies a possible new function for endostatin, the potential cancer-killer that checks blood vessel growth. Within the developing kidney, endostatin may help regulate the branching that establishes the network of urine-collecting tubules. Cells in the ureteric bud divide and change shape to form the plumbing system of the kidney. Because endostatin inhibits blood vessel formation,...

a 78-year-old woman was referred for coronary angiography with the chief complaint of exertional angina and dyspnea of a very long duration during routine daily physical activities. she had a history of poorly controlled hypertension and dyslipidemia. coronary angiography revealed diffuse three-vessel disease. interestingly, an unusual branch was noted originating from the mid shaft of the left...

the carotid is a small mass of chemoreceptor's and sustentacular cells that detects changes in the composition of the arterial blood. the aim of the present study was to identify the size, color, location, blood and nerve supply of the carotid body in makouei sheep. fourteen heads of sheep from both sexes were collected from urmia public slaughter-house. the exact situation and nerve supply of ...

abstract in order to study the effect of planting density and branch pruning on growth, yield and quality of greenhouse muskmelon, a study has been conducted using a factorial experiment in a completely randomized design with three replications and three factors, including cultivar (galia-52 and mirella), branch pruning (1 and 2 branch per plant), and plant density (2, 2.4, 2.8 and 3.6 plants p...

in this paper we consider the non-preemptive variant of a multi-mode resource constrained project scheduling problem (mrcpsp) with mode identity, in which a set of project activities is partitioned into disjoint subsets while all activities forming one subset have to be processed in the same mode. we present a depth-first branch and bound algorithm for the resource constrained project schedulin...

Executive Summary: This study evaluated the relationship between academic outcomes and SAT scores. A descriptive analysis indicated that students with higher SAT scores tend on average to have better academic outcomes (retention, graduation, and cumulative GPA), although this relationship was weaker at the higher end of the SAT score spectrum (i.e. students with very high SAT scores do not nece...