نتایج جستجو برای: a29
تعداد نتایج: 143 فیلتر نتایج به سال:
Up or Out: Research Incentives and Career Prospects of Postdocs in Germany Academic careers in Germany have been under debate for a while. We conduct a survey among postdocs in Germany, to analyze the perceptions and attitudes of postdocs regarding their research incentives, their working conditions, and their career prospects. We conceptualize the career prospects of a postdoc in a life-cycle ...
A 48-year-old woman presented with floaters, photopsia, blurred vision and ocular pain in both eyes of a few days’ duration prior to referral. She had a history of diabetes mellitus for 10 years and was being treated with glibenclamide and metformin. On examination, visual acuity was 20/160 and 20/50 in the right and left eyes, respectively with no significant refractive error. Both pupils were...
Birdshot chorioretinopathy (BSCR) is a rare form of autoimmune uveitis that can lead to severe visual impairment. Intriguingly, >95% of cases carry the HLA-A29 allele, which defines the strongest documented HLA association for a human disease. We have conducted a genome-wide association study in 96 Dutch and 27 Spanish cases, and 398 unrelated Dutch and 380 Spanish controls. Fine-mapping the pr...
A pilot study is reported of HLA-A, B, and C antigens in 141 East African Blacks comprising patients with Burkitt's lymphoma or nasopharyngeal carcinoma, either with active disease or in long-term remission, together with comparable controls. This study forms part of a wider program investigating host factors in these diseases. A protocol was selected for optimal testing of cells processed and ...
A29-year-old man presented with heavy chest pain of 1 hour duration. Two months earlier, after a violent body check while playing American football, he had the same discomfort, albeit to a lesser degree, on slight exertion. Previously, he had been healthy, with no risk factors for coronary artery disease. Physical examination was unremarkable. The ECG showed an extensive acute anterior infarcti...
Viral proteins expressed by EBV-associated tumors provide target Ags for immunotherapy. Adoptive T cell therapy has proven effective for posttransplant EBV-associated lymphoma in which all EBV latent Ags are expressed (type III latency). Application of immunotherapeutic strategies to tumors such as nasopharyngeal carcinoma and Hodgkin's lymphoma that have a restricted pattern of EBV Ag expressi...
We present high-resolution radio images at 1.4 GHz of two Galactic supernova remnants (SNRs), G003.8–00.3 (formerly G003.7–00.2) and G350.0– 02.0 (formerly G350.0-01.8). Although the two objects are very different in appearance, in both cases the radio emission shows a clear bilateral (or “barrel”) morphology for which the axis is parallel to the Galactic Plane. The majority of Galactic SNRs ha...
Associations of MHC ancestral haplotypes with resistance/susceptibility to AIDS disease development.
We tested the association of MHC ancestral haplotypes with rapid or slow progression to AIDS by comparing their frequencies in the French genetics of resistance/susceptibility to immunodeficiency virus cohort with that reported in a control French population. Seven ancestral haplotypes were identified in the genetics of resistance/susceptibility to immunodeficiency virus cohort with a frequency...
Indian population is well known for its genetic diversity. Among the numerous endogamous communities, which are restricted very much by custom, marriage and occupation we have collected 195 unrelated individuals, belonging to Marathi, Gujarathi, Punjabi, South Indian, Christian and Muslim population groups. We present here the HLAA, B, and C locus antigen distribution of these population groups...
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