We characterized multidrug-resistant Pseudomonas aeruginosa strains isolated from patients involved in an outbreak of catheter-associated urinary tract infections that occurred in a neurosurgery ward of a hospital in Sendai, Japan. Pulsed-field gel electrophoresis of SpeI-, XbaI-, or HpaI-digested genomic DNAs from the isolates revealed that clonal expansion of a P. aeruginosa strain designated...

The prevalence of aminoglycoside resistant enzymes has previously been reported and extended-spectrum β-lactamase among Acinetobacter baumannii. To track the risk of multidrug-resistant A. baumannii, the present study aimed to determine the prevalence of carbapenemases in high-level aminoglycoside resistant A. baumannii over two years. A total of 118 strains of A. baumannii were consecutively c...

Non-fermenters are aerobic non-spore forming Gram-negative bacilli that either incapable of catabolized carbohydrates as a source of energy or degrade them via oxidative rather than fermentative metabolic pathways. In the group of non-fermenters Pseudomonas aeruginosa is eminent pathogen followed by Acinetobacter baumanni. Both of these organisms are reported for their intrinsic resistance agai...

Quinolone resistance in members of the Enterobacteriaceae family is mostly due to mutations in the quinolone resistance-determining regions of topoisomerase genes. CTX-M-22 is a member of the CTX-M family which can reduce extended-spectrum β-lactamase (ESBL) production and modulate antibiotic resistance, resulting in low ceftazidime minimum inhibitory concentrations (MICs). There are four diffe...

OBJECTIVES We aimed to evaluate the occurrence and characteristics of plasmid-mediated quinolone resistance (PMQR) genes in KPC-producing (KPC-P) Klebsiella pneumoniae (Kpn) isolates in Tel Aviv Medical Center, Israel. METHODS Forty-seven KPC-P Kpn isolates were studied. Antibiotic susceptibilities were determined by Vitek 2, Etest or agar dilution. Beta-lactamases and PMQR determinants were ...

Pseudomonas aeruginosa is a gram-negative, obligate aerobic bacil which is widespread in world and causes burned hospital infections in humans. Multidrug resistant strains of Pseudomonas aeuginosa (MDR) have been emerged as alarming nosocomial pathogens among burned patients in Tehran (Iran). Integrons play important role in drug resistant in bacteria. Aminoglycosides are common antibiotics whi...

word count = 250 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 Copyright © 2012, American Society for Microbiology. All Rights Reserved. Antimicrob. Agents Chemother. doi:10.1128/AAC.00141-12 AAC Accepts, published online ahead of print on 21 May 2012 on July 6, 2017 by gest httpaac.asm .rg/ D ow nladed fom

OBJECTIVES To investigate the prevalence of aminoglycoside resistance and genes encoding aminoglycoside-modifying enzymes (AME) in blood culture isolates of coagulase-negative staphylococci (CoNS) from neonates. MATERIALS AND METHODS A total of 180 isolates from 148 patients collected in a single neonatal unit over a 12 year period were examined for susceptibility to gentamicin, tobramycin, n...