Results: The findings revealed that petroleum ether extracts possess excellent anti-lice activity .In 15 % concentration seed oil is able to kill 100% lice and 10 and 15 % concentration of seed oil makes nits unable to survive, results were well comparable with standard i.e benzoyl benzoate (25% w/v) as its 10% and 20% concentrations are able to kill 100% lice and deactivated nits. These result...

Anticancer and immunostimulatory properties of tryptic digest peptides of Abrus precatorius agglutinin protein (10kDAGP) have already been reported. Here attempt has been made to further validate anticancer properties of 10kDAGP peptides in Ehrlich's ascites carcinoma (EAC) and B16 melanoma (B16M) bearing mice models and to analyze 10kDAGP by anion exchange chromatography and RP-HPLC for obtain...

The excessive exploitation of medicinal plants during recent years raises the issues regarding their quality, safety and efficacy. In this respect, there has been a rapid increase in the standardization of medicinal plants with therapeutic potential. In spite of the new techniques, identification and evaluation of plant drugs pharmacognostic study is more cheap and reliable. Abrus precatorius L...

A library of 206 extracts from selected South African plants was screened in vitro against a panel of protozoan parasites, Plasmodium falciparum, Trypanosoma brucei rhodesiense, and Leishmania donovani. A CH2Cl2/MeOH (1 : 1) extract of Abrus precatorius L. ssp. africanus strongly inhibited P. falciparum (98 %), T. b. rhodesiense (100 %), and L. donovani (76 %) when tested at a concentration of ...

A protein extract isolated from the seeds of Abrus preca torius L. is shown to exhibit antitumor activity on Yoshida sarcoma (solid and ascites forms) in rats and a fibrosarcoma in mice. The intraperitoneal route of administration is more ef fective than subcutaneous injections. The extract has a direct cytotoxic effect on the tumor cells. Vacuolation and disrup tion of cytoplasm accompanied by...

Abrin, a galactose specific lectin was purified using sepharose 4B affinity column from seeds of Abrus precatorius. It exhibited antitumour activity in mice when used at a sublethal dose of 7.5 micrograms/kg every alternate day for 10 days. Both intralesional and intraperiloneal (i.p.) administration of abrin was effective in reducing solid tumour mass development induced by Dalton's Lymphoma A...