Today there are quite a few widespread misconceptions of exploratory data analysis (EDA). One of these misperceptions is that EDA is said to be opposed to statistical modeling. Actually, the essence of EDA is not about putting aside all modeling and preconceptions; rather, researchers are urged not to start the analysis with a strong preconception only, and thus modeling is still legitimate in ...

Electrodermal activity (EDA) recordings are widely used in experimental psychology to measure skin conductance responses (SCRs) that reflect sympathetic nervous system arousal. However, irregular respiration patterns and deep breaths can cause EDA fluctuations that are difficult to distinguish from genuine arousal-related SCRs, presenting a methodological challenge that increases the likelihood...

BACKGROUND Pretreatment of lignocellulosic biomass is essential to increase the cellulase accessibility for bioconversion of lignocelluloses by breaking down the biomass recalcitrance. In this work, a novel pretreatment method using ethylenediamine (EDA) was presented as a simple process to achieve high enzymatic digestibility of corn stover (CS) by heating the biomass-EDA mixture with high sol...

The highly conserved ectodysplasin A (EDA)/EDA receptor signaling pathway is critical during development for the formation of skin appendages. Mutations in genes encoding components of the EDA pathway disrupt normal appendage development, leading to the human disorder hypohidrotic ectodermal dysplasia. Spontaneous mutations in the murine Eda (Tabby) phenocopy human X-linked hypohidrotic ectoder...

We show that the cooperative reinforcement between hydrogen bonds in guanine quartets is not caused by resonance-assisted hydrogen bonding (RAHB). This follows from extensive computational analyses of guanine quartets (G(4)) and xanthine quartets (X(4)) based on dispersion-corrected density functional theory (DFT-D). Our investigations cover the situation of quartets in the gas phase, in aqueou...

The encounter complex between photoexcited quinones Q* and various aromatic donors (ArH) is observed directly by time-resolved ps spectroscopy immediately before it undergoes electron transfer to the ion-radical pair [Q•-, ArH•+]. The encounter complex (EC) is spectrally characterized by distinctive (near IR) absorption bands, and its temporal evolution is established by quantitative kinetics a...

Fibronectin is a crucial extracellular matrix (ECM) protein regulating ECM-dependent cell adhesion, migration, and differentiation. Besides being deposited as insoluble fibrils in tissues, it is also produced as soluble dimers by the liver and released in plasma. The presence of fibronectin in atherosclerotic plaques was described more than 20 years ago and plasma fibronectin has been shown to ...