The performance of an intraocular lens is determined by several factors such as the surgical technique, surgical complications, intraocular lens biomaterial and design, and host reaction to the lens. The factor indicating the biocompatibility of an intraocular lens is the behavior of inflammatory and lens epithelial cells. Hence, the biocompatibility of intraocular lens materials is assessed in...

PURPOSE To investigate changes of crystalline lens position during accommodation in children with emmetropia, myopia, and hyperopia. METHODS A total of 188 children (372 eyes) from 4 to 19 years old (mean age 11.3+/-4.43) with cycloplegic refractive error within a range +9.00 D to -9.00 D were enrolled. After a general ophthalmic examination, ultrasound biometry was performed, with the eye at...

Accommodation is a dioptric change in power of the eye that occurs to allow near objects to be focused on the retina. The ability to accommodate is lost with increasing age in humans and monkeys. This phenomenon, called presbyopia, is the most common human ocular affliction, and its pathophysiology remains uncertain. The progressive loss of human accommodative amplitude begins early in life and...

PURPOSE To determine the biometry of anterior segment dimensions of the human eye on both horizontal and vertical meridians with extended scan depth optical coherence tomography (OCT) during accommodation. METHODS Twenty pre-presbyopic volunteers, aged between 24 and 30, were recruited. The ocular anterior segment of each subject was imaged using an extended scan depth OCT under non- and 3.0 ...

INTRODUCTION Spontaneous dislocation of intraocular lens with bag is rare. METHODS We report a case of a 56-year-old male who presented with spontaneous anterior dislocation of an in-the-bag intraocular lens 3 years after manual small incision cataract surgery. He had undergone manual small incision cataract surgery with foldable acrylic intraocular lens implantation, and 18 months after cata...

Purpose Insufficient accommodative response is assumed to result in myopia progression. We have investigated if the accommodative lag in myopes is different between a single vision lens (SVL) and the progressive addition lens PAL 2, clinically trialled for its ability to reduce progression of myopia, and if there exist differences in accommodative lag between PAL 2 and other PALs with the same ...

AIM To understand the effect of the geometric and material properties of the lens on the age-related decline in accommodative amplitude. METHODS Using a non-linear finite-element model, a parametric assessment was carried out to determine the effect of stiffness of the cortex, nucleus, capsule and zonules, and that of thickness of the capsule and lens, on the change in central optical power (...

In order to determine the importance of lens actin filament configuration to lens accommodation, the pattern of actin filaments in the epithelium was studied in human lenses from different decades of life spanning the accommodative and non-accommodative years. Polygonal arrays of microfilaments were demonstrated in whole mounts of epithelium from normal and cataractous lenses using rhodamine ph...

BACKGROUND Improvement in surgical devices and intraocular lenses has made modern cataract surgery a safe procedure with decreasing complication rates. Intraocular lens dislocation is a serious complication after cataract surgery. Although most dislocations occur during the first week postoperative period, late intraocular lens dislocation occurring 3 months or later post-surgery has been repor...