BACKGROUND Practice guidelines for the management of congestive heart failure (CHF) emphasize the need for assessment of left ventricular function and treatment with angiotensin-converting enzyme (ACE) inhibitors. However, previous studies have shown that many patients do not receive these tests or medications. The objective of this study was to evaluate the compliance of physicians at a large ...

BACKGROUND There is compelling experimental evidence that autologous skeletal muscle (SM) cell transplantation improves postinfarction cardiac function. This study assessed whether this benefit is still manifested in the clinically relevant setting of a treatment by ACE inhibitors. METHODS AND RESULTS A myocardial infarction was created in 99 rats by coronary artery ligation. They were divide...

The benefits of ACE inhibitors as standard treatment for patients with overt heart failure due to ventricular dilatation and systolic dysfunction are proved beyond reasonable doubt, at least when a diuretic has been used to control symptoms. More recent studies have suggested that ACE inhibitors may delay or prevent the onset of heart failure requiring diuretics in patients with obviously impai...

Angiotensin-converting enzyme (ACE) inhibitors appear to possess unique cardioprotective benefits, even when used in patients without high blood pressure or left ventricular dysfunction (the traditional indications for ACE inhibitor therapy). The ACE inhibitors improve endothelial function and regress both left ventricular hypertrophy and arterial mass better than other antihypertensive agents ...

Sir, Angiotensin-converting enzyme (ACE) inhibitors are the most frequently prescribed antihypertensive drugs. Their effects on both hypertension and heart failure are highly beneficial. However, one has to be aware of the potential side effects, approximately 50% occurring in the skin. While angioedema is a well-known adverse cutaneous reaction to ACE inhibitors, other skin reactions are uncom...