نتایج جستجو برای: aceclofenac optimization

تعداد نتایج: 318491  

2012
G VIJAYA

The purpose of the present research was to produce a quick/slow biphasic delivery system for aceclofenac. A dual component tablet made of a sustained release tabletted core and an immediate release tabletted coat was prepared by direct compression. Both the core and the coat contained a model drug aceclofenac. The sustained release effect was achieved with polymers hydroxypropyl methylcellulose...

2014
Jaganmohan Somagoni Cedar H. A. Boakye Chandraiah Godugu Apurva R. Patel Henrique Antonio Mendonca Faria Valtencir Zucolotto Mandip Singh

AIM The objective of this study was to formulate and evaluate a unique matrix mixture (nanomiemgel) of nanomicelle and nanoemulsion containing aceclofenac and capsaicin using in vitro and in vivo analyses and to compare it to a marketed formulation (Aceproxyvon). METHODS Nanomicelles were prepared using Vitamin E TPGS by solvent evaporation method and nanoemulsion was prepared by high-pressur...

2012
Thiruganesh Ramasamy Umadevi Subbaih Khandasamy Suresh Shanmugam Himabindhu Ruttala

The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 as ...

2012
Dilip Patel Sandipan Dasgupta Sanjay Dey Y. Roja Ramani Subhabrata Ray Bhaskar Mazumder

The aim of this study was to prepare nanostructured lipid carriers (NLC)-based topical gel of aceclofenac for the treatment of inflammation and allied conditions. Stearic acid as the solid lipid, oleic acid as the liquid lipid, pluronic F68 as the surfactant, and phospholipon 90G as the co-surfactant were used. NLCs were prepared by melt-emulsification, low-temperature solidification, and high-...

Journal: :Pakistan journal of pharmaceutical sciences 2014
Irin Dewan Salim Miah S M Ashraful Islam Sohel Rana

The aspire of this attempt was to design and evaluate aceclofenac loaded sustained release microspheres by emulsion solvent evaporation method, using different polymers like Ethyl cellulose (EC), Kollidon SR (KSR), Eudragit RS 100, Eudragit RL 100 and Hydroxypropylmethyl Cellulose (HPMC K100M). Microspheres were prepared using different stirring rate (1200, 1500, 2000rpm) and larger microsphere...

2003
B.Gowramma S. Rajan S. Muralidharan S. N. Meyyanathan B. Suresh

A simple, selective, rapid, precise and economical reverse phase high performance liquid chromatographic method has been developed for the simultaneous estimation of paracetamol and diclofenac potassium from pharmaceutical formulation. The method was carried out on a Phenomenex LUNA C18 (25 cm x 4.6 mm i.d., 5 μ) column with a mobile phase consisting of acetonitrile: sodium dihydrogen ortho pho...

Journal: :Expert opinion on pharmacotherapy 2004
Erik Legrand

Aceclofenac (Almirall Prodesfarma SA) is an oral NSAID that is effective in the treatment of painful inflammatory diseases and has been used to treat > 75 million patients worldwide. It has proved as effective as diclofenac, naproxen and piroxicam in patients with osteoarthritis, diclofenac, ketorolac, tenoxicam and indomethacin in patients with rheumatoid arthritis and tenoxicam, naproxen and ...

Journal: :Indian Journal of Dermatology 2018

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