Pd-catalyzed asymmetric allylic sulfonation of di-aryl-substituted allylic acetates with sodium sulfite (Na2SO3) in THF-H2O at room temperature was described. This method directly provided allylic sulfonic acids in up to excellent yield and enantioselectivity.

The efficient synthesis of functionalized enamines including β-enaminoesters was effectively accomplished by the direct condensation of functionalized sp(3) carbanions such as acetates with formamides using in situ generated HMDS base from catalytic cesium fluoride and stoichiometric tristrimethylsilylamine.

Controlling nanocomposite composition and morphology is a vital step toward designing new and advanced materials. The current work presents the results of an experimental investigation of the use of mixed-phase reactants for the synthesis of nanocomposite materials. Gas-phase tetramethyltin was used as a precursor for tin dioxide (SnO2). Metal additives were introduced to the SnO2 synthesis sys...

Asymmetric coupling proceeds efficiently between propargylic acetates, cycloalkenes and electron-rich heteroarenes including indoles, pyrroles, activated furans thiophenes. 2,3-Disubstituted tetrahydrofurans pyrrolidines are produced in trans configuration excellent enantiomeric ratios. The reaction via Wacker-type attack of nucleophilic on alkenes by allenyl PdII species.

A chiral tridentate ketimine P,N,N-ligand has been successfully applied in the copper-catalyzed enantioselective propargylic substitution of propargylic acetates with a variety of β-dicarbonyl compounds, in which excellent enantioselectivities (up to >99% ee) and high yields have been obtained.

The use of [(IPr)AuOH] permits the generation of gold(i)-amine complexes by a silver-free protocol. These in situ or well-defined complexes are used in a straightforward synthetic route to substituted allenes from propargylic acetates. The catalytic activity can be modulated as a function of the nature of the ligand bound to the gold-NHC moiety.