The n-hexane (HE), dichloromethane (DC), methanol (ME), ethanol 70% (ET), and methanol with Soxlhet apparatus (MS) extracts of Stachys lavandulifolia aerial parts were screened for their potential tyrosinase, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity. ET and MS inhibited tyrosinase with IC50 values of 33.4 and 42.8 μg/mL, respectively. The phytochemical in...

Objective: Acteoside (ACT) has been reported to regulate the inflammation and immune response. The study aims explore effect of ACT on renal fibrosis in unilateral ureteral obstruction (UUO) rats. Methods: Eighteen Sprague-Dawley rats were randomly divided into 3 groups: sham group, opened abdominal cavity sutured abdominal; UUO performed surgery; + (40 mg/kg) was given by gavage every day afte...

The MTT assay, as a screening method, has been widely used to measure the viability and proliferation of cells. However, it should be noted that MTT assay may not accurately reflect the effect of Cistanche tubulosa ethanolic extract on EA.hy926 cells viability. To investigate and identity the components responsible for the contradictory observations of the MTT assay, echinacoside and acteoside,...

Paulownia tomentosa is a large indecidous tree planted mostly for its fast growing wood and decorative purposes. The tree is also used in traditional Chinese medicine. As a part of our study of natural polyphenols, the fruits of Paulownia tomentosa were extracted by EtOH and than subjected to liquid/liquid extraction. Fractions were analysed by TLC and HPLC to determine presence of phenolic sub...

Clerodendrum serratum Linn. (Family: Verbenaceae) is very widely distributed in tropical and subtropical regions of the world. Ethno-medicinal importance of the plant has been reported in various indigenous systems of medicines like Ayurveda, Siddha and Unani for the treatment of various life-threatening diseases such as syphilis, typhoid, cancer, jaundice and hypertension. Some of the chief co...

Bharngi is one of the drugs of Ayurvedic meteria medica which is mainly indicated in the respiratory disorders. One the botanical sources of Bharngi is Clerodendrum serratum Linn. another species Pygmaeopremna herbacea is being in use for Bharngi. Clerodendrum serratum Linn. (Family: Verbenaceae) is very widely distributed in tropical and subtropical regions of the world. In Ayurveda it is used...

From the leaves of Phlomis aurea, two new iridoids of unique structures named 3-epiphlomurin (1) and phlomurin (2), a new megastigmane glucoside phlomuroside (3) and a new benzyl alcohol glycoside having the structure benzyl alcohol-O-beta-xylopyranosyl-(1-->2)-beta-glucopyranoside (4) have been isolated together with four known iridoids auroside, lamiide, 8-epiloganin and ipolamiide, two known...

Premna serratifolia Linn. (syn: Premna integrifolia) is one the most widely used plant in the Ayurvedic system of medicine. Several pharmacological activities including antioxidant effects and phytochemical investigations have been previously reported for the various parts of plant, except the root woody tissues. In the present study, the antioxidant activity and active principle of the root wo...