نتایج جستجو برای: acute and chronic toxicity

تعداد نتایج: 17050953  

Journal: :Journal of Biomedical and Pharmaceutical Research 2022

The present study is designed to evaluate the safety of aqueous: methanolic (40:60) extract Solanum xanthocarpum whole plant (SXWP) by determining its potential toxicity after acute and subacute administration in male wistar albino rats. Medicinal plants might deliver a few organic activities people, but generally very little known about their toxicity. Though, should be overriding criterion se...

Journal: :jundishapur journal of natural pharmaceutical products 0
leila etemad pharmaceutical research center, mashhad university of medical sciences, mashhad, ir iran zahra oskouei shirvan departments of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran naser vahdati-mashhadian medical toxicology research center, department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran seyed adel moallem pharmaceutical research center, medical toxicology research center, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran reza zafari departments of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran hossein hosseinzadeh pharmaceutical research center, department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran; pharmaceutical research center, department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, ir iran. tel: +98-5138819042, fax: +98-513882 3251

conclusions results from the present study elucidated that treatment with the aqueous extract of l. citriodora leaves was well tolerated via daily ip injection at doses up to 200 mg/kg for a period of 21 days and did not produce any toxicity. the safety of l. citriodora aqueous extract was also confirmed by cell viability assay. objectives the present study evaluated the acute, subacute, and ce...

Journal: :iranian journal of pediatric hematology and oncology 0
azam sadat hashemi assistant professor of pediatric hematology & oncology of shahid sadoughi university of medical sciences,yazd (hematolog fateme kargar medical doctor (hematology, oncology & genetics research center of shahid sadoughi university of medical sciences, yazd)سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences) azade souzani سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences) n hazar general practitioner

abstract objective immune thrombocytopenic purpura (itp) manifests as an easy bruising or extravasation of blood from capillaries into skin and mucous membranes. the characteristics of acute itp in infants have rarely been described. in order to better understand acute itp in infants, the characteristics of the disease at this age group was investigated. material and methods the present descrip...

Journal: :Environmental toxicology and chemistry 2004
Karel A C De Schamphelaere Colin R Janssen

In this study, we developed a toxicity model predicting the long-term effects of copper on the reproduction of the cladoceran Daphnia magna that is based on previously reported toxicity tests in 35 exposure media with different water chemistries. First, it was demonstrated that the acute copper biotic ligand model (BLM) for D. magna could not serve as a reliable basis for predicting chronic cop...

Afshin Peirovi, Mohammad Kamalinejad, Mohammad Sayyah,

Cuminum cyminum Linn. (Umbelliferae) is a plant, which has been used as a toothache remedy in folk medicine of Iran. In this study, the potential anti-nociceptive and anti-inflammatory activities of the fruit essential oil of C. cyminum has been evaluated in chemical (formalin test) and thermal (tail-flick test) models of nociception and formalin model of acute inflammation in rats and mice. Th...

Journal: :international journal of advanced biological and biomedical research 2013
vahed kiyani mohammad hasan hosynzadeh mohammad ebrahimpour

all aquatic organisms are directly or indirectly affected by the physical characteristics of their environment, especially the chemical composition of the water. the high concentration levels, damage tissues and interfere with the normal growth and proliferation. the aim of this research was to investigation acute toxicity of znso4 and cucl2 to gambusia holbrooki by static bioassays at differen...

Journal: :The Tohoku Journal of Experimental Medicine 1971

Journal: :iranian journal of science and technology (sciences) 2004
s. akbari

the acute toxicity of a malaysian crude oil to red snapper, lutjanus argentimaculatus, blacktiger shrimp and penaeus monodon were investigated. the animals were exposed to water solublefractions (wsf) of crude oil in a flow-through bioassay system and the toxicants were analyzed by gaschromatography (gc) and gas chromatography and mass spectrometer (gc-ms). the 96 h lc50 valuesof the wsf of cru...

Journal: :international journal of aquatic biology 0
abdul rauf government superior degree science college, shah faisal colony, karachi, pakistan

malathion is one of the most commonly used pesticides in agriculture. this study was aimed to investigate the acute toxicity of malathion as an aquatic pollutant on the behavior and hematological indices in indian carp ( cirrhinus mrigala ). a static experiment was conducted and 1, 24, 48, 72 and 96 hrs lc 50 values of malathion for the test fish were estimated as 14.55 mg/l, 12.48 mg/l, 11.56 ...

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