نتایج جستجو برای: acute myeloblastic leukemia
تعداد نتایج: 688174 فیلتر نتایج به سال:
Objective: Lymphoid enhancer-binding factor-1 (LEF1) is one of the key regulators lymphocyte proliferation and its aberrant expression a prognostic factor for lymphoid or myeloid malignancies. In this study, we focused on LEF1 isoforms in several hematological malignancies found tissue-specific differential full-length (FL)-LEF1 gene tumor suppressor (∆LEF1) variant. Material Method: Fifty-thre...
A correlation was made between chromosomal findings in the marrow of AML patients obtained during the course of the disease, some of the clinical and cytologic features, and the survival span of these patients. The median survival time for each patient was obtained by the use of log-probability paper. Of the 69 patients with AML studied, 29 showed abnormal metaphases in the marrow at least once...
A 64-yr-old female developed acute myeloblastic leukemia following radiation and drug therapy for colon carcinoma. The patient was heterozygous for glucose-6-phosphate dehydrogenase (G-6-PD) and displayed types A and B isoenzymes in nonhematopoietic tissue. In contrast, only type B G-6-PD was observed in peripheral blood white cells. In addition, a karyotypic abnormality was found in peripheral...
Background and Aim: APL is a Prevalent leukemia that Approximately included 5-10% of patients with acute myeloblastic leukemia. ATRA and recently arsenic is used for treatment. ATRA leadsto resistance to treatment and arsenic is toxic in high doses.AZT induce cell death in different ways. The purpose of this study was Assessment of effect of AZT, a telomerase inhibitor, on NB4 cell line (APL ce...
Pyrimethamine, a substituted pyrimidine trations of pyrimethamine were 10-25% with potent folate antagonistic properof the simultaneous plasma concentraties, was given orally to treat two epitions. Considerations regarding lipid solsodes of meningeal leukemia in a longubility, body distribution, and easily term survivor with acute myeloblastic reversible toxicity of pyrimethamine sugleukemia. R...
Two patients with acute myeloblastic leukemia (AML) with double minute chromosomes (dmins) are described. One patient had dmins in approximately one-third of bone marrow cells examined at diagnosis; no other karyotypic changes were observed. The dmins disappeared when the patient achieved a complete remission. The second patient developed acute leukemia as a second cancer, having previously rec...
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