objective(s) recent studies revealed the neuroprotective effects of epigallocatechin gallate (egcg) on a variety of neural injury .the purpose of this study was to determine the effects of egcg on the tissue lipid peroxidation after spinal cord injury (sci). materials and methods rats were randomly divided into four groups of 7 rats each as follows: sham-operated group, trauma group, and egcg-t...

Objective(s): To reach an evidence-based knowledge in the context of the temporal-spatial pattern of neuronal death and find appropriate time of intervention in order to preserve spared neurons and promote regeneration after traumatic spinal cord injury (TSCI). Materials and Methods: The study design was based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA)-guided...

Spinal cord injury may cause loss of cardiovascular reflexes mediated by sympathetic drive due to interruption in the supraspinal control of spinal sympathetic motoneurons. The aim of this study was to analyze sympathovagal balance after acute spinal cord injury demonstrated by linear measures in time and frequency domain of heart rate variability (HRV). The study included 40 tatraplegic patien...

I t is time to clear the confusion about the utility of steroids in cases of acute spinal cord injury. A committee of Canadian neurosurgical and orthopedic spine specialists, emergency physicians and physiatrists (listed at the end of the article) has reviewed the evidence and concluded that high-dose methylprednisolone infusion is not an evidence-based standard of care for patients with such a...

The most common cause of spinal cord injury are high impact trauma, which often result in some motor impairment, sensory or autonomic a greater or lesser extent in the distal areas the level of trauma. In terms of survival and complications due to sequelae, veterinary patients have a poor prognosis unfavorable. Therefore justified the study of experimental models of spinal cord injury productio...

OBJECTIVE The purpose of this study was to determine the incidence of missed and mismanaged injuries of the spinal cord, to identify factors contributing to a failure to recognize such injuries, and to assess the consequences of such failures. METHODS Missed and mismanaged injuries were defined using previously validated statements. All medical records and radiographs of patients with acute t...

During aortic surgery, interruption of spinal cord blood flow might cause spinal cord ischemia-reperfusion injury (IRI). The incidence of spinal cord IRI after aortic surgery is up to 28%, and patients with spinal cord IRI might suffer from postoperative paraplegia or paraparesis. Spinal cord IRI includes two phases. The immediate spinal cord injury is related to acute ischemia. And the delayed...

INJURY to the spinal cord is devastating and catastrophic. Its unfortunate sequelae have been recognized since early Egyptian times [l]. Since damage to the spinal cord almost always results in permanent loss of sensory and motor functions below the level of the injury, the best solution to the problem of spinal cord injuries is prevention. There are no published data on the incidence of trauma...

pediatric neurological disorders including muscular dystrophy, cerebral palsy, and spinal cord injury are defined as a heterogenous group of diseases, of which some are known to be genetic. the two significant features represented for stem cells, leading to distinguish them from other cell types are addressed as below: they can renew themselves besides the ability to differentiate into cells wi...