background : to identify correlates related to retention time of a cohort study of the opioid-dependent patients participating in the methadone maintenance treatment (mmt) program offered by a major addiction treatment clinic in tehran, iran between april 2007 and march 2011. methods : several parametric survival models assuming weibull, log-normal and log-logistic distributions were compared t...

results results showed that there was a significant difference between the experimental and control groups in terms of depression and temping beliefs (p < 0.0001). in other words, the results showed that cognitive-behavior therapy reduces depression and improves craving beliefs of abusers under methadone maintenance treatment. objectives this study aimed at investigating the effectiveness of co...

There are currently effective, U.S. Food and Drug Administration (FDA)-approved therapies for alcohol, nicotine, and opioid addiction. In some cases these therapeutics were rationally designed and tested using a combination of various animal models of addiction. In many cases, however, effective drug therapies for addiction were derived from the testing of compounds developed for other CNS diso...

New scientific knowledge and effective, evidence-based interventions have provided health leaders and policymakers a remarkable paradigm to guide the development of addiction treatment services around the world. The definition of addiction as a brain disease, validated screening and assessment tools, medication-assisted treatment, and effective behavioral treatments have served as vehicles for ...

Privately funded addiction treatment programs were surveyed to increase understanding of assessment and current treatment options for patients with co-occurring substance use and eating disorders. Data were collected from face-to-face interviews with program administrators of a nationally representative sample of 345 private addiction treatment programs. Although the majority of programs report...

background: the retention rates are important factors in methadone maintenance treatment. this study was performed with aims to determine the attitude and subjective norms in methadone treatment maintenance among kohgilouyeh and boyer ahmad’s province addict who referred addiction treatment centers. methods: this research was a cross-sectional study that done among men’s addicted who are receiv...

Addiction or substance dependence is a psychiatric disorder that affects many individuals in the general population. Different theories concerning the neurobiological aspects of addiction have been proposed. Special attention has been paid to models concerning dysregulation of the reward circuit and the inhibitory control system within the cortico-basal ganglia-thalamocortical pathways. In the ...

Marine cone snails produce venoms (Conotoxins: CT) that have attracted interest as leads in drug design. CT are small peptides containing one or more disulfide bonds. α-CT specifically target different isoforms of nicotinic acetylcholine receptors (nAChR). In view of the important role of nAChR in normal and disease physiology such as addiction disorders, specific targeting of the relevant nACh...

In this article we summarized the recent research of the food addiction, diagnosis, treatment and prevention, which is carried out in this area. The concept of food addiction is new and complex, but proven to be very important for understanding and solving the problem of obesity. First part of this paper emphasizes the neurological studies, whose results indicate the similarity of brain process...