نتایج جستجو برای: adipokines
تعداد نتایج: 4634 فیلتر نتایج به سال:
After more than a half century of efforts, cancer remains the leading cause of death globally, second only to cardiovascular diseases. The World Health Organization estimates that 84 million people will die from cancer in the next ten years if no action is taken (http://www.who.int/cancer). Obesity appears to play important roles not only in cardiovascular and metabolic diseases, but also in ca...
BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARγ) has direct and indirect function in adipokines production process. We aimed to assess the possible influence of circulating PPARγ on relative risk of metabolic syndrome and also examine the association between circulating PPARγ and adipokines levels among obese subjects. METHODS A total of 96 obese subjects (body mass index (...
Significant bone remodeling with disordered osteoclastogenesis has been implicated in the pathogenesis of psoriatic arthritis (PsA). And there is a high prevalence of the metabolic syndrome (MS) in PsA patients. Adipokines, especially leptin and adiponectin, have recently been reported to be involved in the development and regulation of some autoimmune diseases. In this study, we examined the a...
Adipokines are a large group of polypeptide hormones secreted by white adipose tissue able to interact through different receptors with several organs, including liver, central nervous system and gonads. In this review, we will focus on the adipokines that mediate their effects G protein-coupled receptors, namely apelin chemerin. Firstly, review structure (APJ for apelin, CMKLR1, GPR1 CCRL2 che...
BACKGROUND Blood adipokines are associated with breast cancer risk; however, blood-breast adipokine correlations and factors that explain variation in adipokines are unknown. METHODS Plasma (n = 155) and breast (n = 85) leptin and adiponectin were assessed by immunoassays in women with no history of cancer. Multivariable-adjusted regression models were used to determine breast adipokine assoc...
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