CONTEXT Homosexual and bisexual men infected with human immunodeficiency virus (HIV) are at increased risk for human papillomavirus-related anal neoplasia and anal squamous cell carcinoma (SCC). OBJECTIVE To estimate the clinical benefits and cost-effectiveness of screening HIV-positive homosexual and bisexual men foranal squamous intraepithelial lesions (ASIL) and anal SCC. DESIGN Cost-eff...

Cost-effectiveness analysis made its first appearance in the health care literature more than 4 decades ago. In Britain, the National Institute of Clinical Excellence (NICE) explicitly considers cost per quality-adjusted life year (QALY) gained among its criteria for coverage recommendations to the National Health Service; some observers have inferred that explicit criteria such as £30,000 per ...

PURPOSE To demonstrate the application of Disability Adjusted Life Year (DALY) as an aid in health outcome measures to evaluate the epilepsy disease burden in rural China and to provide Chinese data to achieve a better understanding of disease burden due to epilepsy. METHODS The DALY is the sum of the number of years of survival with disability (Years Lived with Disability, YLD) and the numbe...

OBJECTIVE We estimated the disability-adjusted life-year (DALY) burden of abusive head trauma (AHT) at ages 0 to 4 years in the United States. METHODS DALYs are computed by summing years of productive life that survivors lost to disability plus life-years lost to premature death. Surveying a convenience sample of 170 caregivers and pediatricians yielded health-related disability over time acc...

Disability-adjusted life year (DALY) is a metric that combines both fatal and non-fatal health problems into a single number. It is the primary metric used by the World Health Organization to assess the global burden of disease, and the metrics for cancer were published in GLOBOCAN2008, which is a project to estimate the incidence, mortality, prevalence and DALY for major types of cancers, at n...

We design and conduct a stated-preference survey to estimate willingness to pay (WTP) to reduce foodborne risk of acute illness and to test whether WTP is proportional to the corresponding gain in expected quality-adjusted life years (QALYs). If QALYs measure utility for health, then economic theory requires WTP to be nearly proportional to changes in both health quality and duration of illness...