In this study we analyzed how IT support can be established for the treatment and documentation of advanced life support (ALS) in a hospital. In close collaboration with clinical researchers, a running prototype of an IT solution to support the clinical decisions in ALS was developed and tried out in a full scale simulation environment. We have named this IT solution the CardioData Prototype.

This article describes the development of a new regulatory model for advanced practice nursing. The history of nursing licensure is detailed to provide a perspective of the differences in the way that advanced practice roles evolved as a result of external forces and patient needs without the direct control of regulators and the resulting variations in the interpretation and implementation of t...

the recognition of apoptotic cells by phagocytes is a complex, yet highly orchestrated event. Many receptors have been identified that recognize phosphatidylserine (pS; Fig 1)—which is exposed on early apoptotic cells—leading to downstream signalling and apoptotic cell engulfment. in this issue of EMBo reports, the receptor for advanced glycation endproducts (ragE) is described as a new pS rece...

Most cancer patients suffering from some form of advanced or locally advanced cancer will be treated with anticancer agents to stop the natural evolution of the disease. Anticancer agents developed over the last four decades behave as cytotoxic drugs inducing tumor regression, sometimes also resulting in prolongation of survival. Historically, the direct therapeutic efficacy of such treatments ...

International Partnership for Microbicides, , Silver Spring, Maryland, USA; Huntingdon Life 6 Sciences, Huntingdon Research Centre, Huntingdon, Cambridgeshire, UK; ABL B.V., Assen, The 7 Netherlands; University of Pittsburgh, Magee Womens Research Institute, Pittsburgh, PA,USA. 8 9 Running Head: Sheep model of microbicide safety and pharmacokinetics 10 11 # Address correspondence to Jonathon D....

Credentialing of advanced practice registered nurses (APRNs) in acute care settings is an essential practice, but care must be taken to ensure that full utilization of the scope of practice and capacity of APRNs is attained. The process of credentialing and privileging involves the verification of required education, licensure, and certification to practice as an APRN along with the recognition...