background: renal failure is an important adverse effect of drug poisoning. determining the prevalence and etiology of this serious side effect could help us find appropriate strategies for the prevention of renal failure in most affected patients. objectives: the present study is aimed to identify drugs that induce renal failure and also to find the prevalence of renal failure in patients refe...

abstract background peripheral blood vessels, due to availability are used for many years in cancer patients, however in patients with potentially harmful drugs to skin (vesicant drugs) or difficult accessibility to vessels, the use of implantable port (totally implantable venous access port-tivap)devices with central vascular access are important.  materials and methods in this retrospective s...

abstract background some researches have shown the association between iron deficiency and migraine headache in adults. the aim of present study was to evaluate efficacy of ferrous sulfate treatment on migraine headaches of 5-15 years old migraineur children with iron deficiency. materials and methods in a quasi- experimental study, monthly frequency, severity, duration and disability of headac...

detection of adverse drug reactions (adrs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. spontaneous reporting of adrs is scare and several obstacles to such reporting have been identified formerly. this study aimed to determine the role of clinical pharmacy residents in adr reporting within a hospital setting.clinical pharmacy resi...

the absence of cerebrospinal fluid (csf) pleocytosis in invasive meningococcal disease (imd) has been associated with an increased risk of death. it is unknown whether patients who lack a cellular response to central nervous system (cns) infection are at the same risk of adverse outcome as patiens without cns infection. to determine the frequency of presentation and outcome of three groups of c...

introduction: endometrial cancer is the most common pelvic malignancy in women. approximately 7,000 women die from this disease every year. although most patients can be treated with appropriate therapies, there is insufficient data regarding the choice of the best adjuvant therapy after a surgical procedure in advanced endometrial cancer cases. it seems that radiotherapy or chemotherapy alone ...

conclusions no evidence-based guidelines exist on the use of analgesics in patients with liver disease and cirrhosis. as a result pain management in these patients generates considerable misconception among health care professionals, leading under-treatment of pain in this population. providing concrete guidelines toward the administration of these agents will lead to more efficient and safer p...

background and objectives: pharmacovigilance is central to the control of the menace of adverse drugs reactions. despite the fact that development of policy and practice framework to improve patients’ safety partly rely on availability of authentic data on pharmacovigilance activities, knowledge about pharmacovigilance activities among healthcare professionals in nigeria is limited. to help fil...

patients and methods this cross-sectional study on 71 patients with ms was carried out between 2010 and 2012, in an iranian population. demographic and pharmacological variables were recorded in d-base. statistical analyses were performed using spss for windows. results the females/males sex ratio within the study population was 3.17: 1. the mean age of females was 32.2 years old (range 20 - 45...

background pharmacovigilance (pv) data are crucial for ensuring safety and effectiveness of medicines after drugs have been granted marketing approval. this paper describes the pv systems of india, uganda and south africa based on literature and key informant (ki) interviews and compares them with the world health organization’s (who’s) minimum pv requirements for a functional national pv syste...