AIMS To explore the usefulness of data derived from observational studies on adverse drug reactions (ADRs) in defining and preventing the risk of pharmacological interventions in children in different health care settings. METHODS A systematic review of studies on ADRs in hospitalized children, in outpatient children, and on ADRs causing paediatric hospital admissions was performed. Studies w...

Objective: To study the clinical spectrum of cutaneous adverse drug reactions (ADRs) in hospitalized patients and to establish a causal link between the drug and the reaction by using WHO causality definitions. Material and Methods: A prospective hospital-based study over a period of one year (October 1, 2002 to September 30, 2003) was carried out by the Department of Pharmacology in the Depart...

BACKGROUND & OBJECTIVES Several studies have reported adverse drug events ranging from 5 to 35 per cent in all age group from outpatient setting. However, adverse drug reactions (ADRs) particularly among a large sample of ambulatory elderly patients in India has not been reported. This study has attempted to identify ADRs and assessed their causality, preventability and severity, and also their...

INTRODUCTION Recognizing adverse drug reactions (ADRs) is becoming more important in clinical practice.  OBJECTIVE To determine the frequency of adverse drug reactions and ADR suspicions among the population affiliated to the Colombian health system and to describe the drugs, reactions and associated variables.  MATERIALS AND METHODS We revised ADRs and ADRs suspicion databases from drugs d...

Adverse Drug Reaction (ADR) is one of the most important issues in the assessment of drug safety. In fact, many adverse drug reactions are not discovered during limited premarketing clinical trials; instead, they are only observed after long term post-marketing surveillance of drug usage. In light of this, the detection of adverse drug reactions, as early as possible, is an important topic of r...

Adverse drug reactions (ADRs) remain a challenge in modern healthcare, particularly given the increasing complexity of therapeutics, an ageing population and rising multimorbidity. This article summarises some of the key facts about ADRs and explores aspects relating to their prevention, diagnosis, reporting and management in current clinical practice.

Aim: Present study was carried out to assess the incidence of adverse drug reactions (ADR) and assessment of causality and severity associated with reported suspected ADRs. Materials and Methods: A prospective cross sectional spontaneous reporting study was conducted over a period of six months in inpatients of Surgery wards of Prince bijaysingh memorial (PBM)Hospital ,Bikaner Rajasthan. Naranj...

Adverse Drug Reaction (ADR) is one of the most important issues in the assessment of drug safety. In fact, many adverse drug reactions are not discovered during limited pre-marketing clinical trials; instead, they are only observed after long term post-marketing surveillance of drug usage. In light of this, the detection of adverse drug reactions, as early as possible, is an important topic of ...

INTRODUCTION Adverse drug reactions associated with efavirenz (EFV) therapy are poorly described beyond the first year of treatment. We aimed to describe the incidence and predictors of EFV-related adverse drug reactions (ADRs) in a cohort of adult Nigerian HIV-infected patients on antiretroviral therapy (ART). METHODS This retrospective cohort study utilized clinical data of HIV-1 infected a...

The present prospective observational study was carried out in a tertiary care hospital in New Delhi, India from May 2014 to June 2015 to report adverse drug reactions (ADRs) in patients with type 2 diabetes mellitus (T2DM) using antidiabetic drugs. A total of 220 patients (121 males, 99 females) were enrolled. ADRs were recorded on the prescribed form. Causality and severity assessment was don...