Non-melanoma skin cancer (NMSC) is the most common malignancy among the Caucasian population. Photodynamic therapy (PDT) is gaining popularity for the treatment of basal cell carcinoma (BCC), Bowen's disease (BD) and actinic keratosis (AK). A topical or systemic exogenous photosensitiser, results in selective uptake by malignant cells. Protoporphyrin IX (PpIX) is produced then activated by the ...

Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), known as nonmelanoma skin cancer (NMSC), are the most common cancers worldwide. Although many factors are involved in the pathogenesis of NMSC, UV radiation is an important risk factor. A fundamental question in skin cancer research is whether varying doses of total UV radiation influence key characteristics of NMSC. The hypothesis t...

A rare case report of Aggressive Digital Adenocarcinoma (ADPCa) is presented complete with a literature review encompassing lesions that pose potential diagnostic challenges. Similarities between basal cell carcinoma (BCC), marjolin's ulceration/squamous cell carcinoma (MSCC) and ADPCa are discussed. This article discusses potential treatment options for ADPCa and the need for early biopsy when...

The ideal classification of basal cell carcinoma (BCC) should be able to identify subtypes which correlate with clinical behaviour and treatment requirements. Unfortunately, however, such a classification has yet to be defined. In the interim, the currently most favoured classification is one based predominantly on histological growth pattern. This classification contributes to the useful conce...

The evaluation of 14F7 Mab (anti-N-glycolyl GM3 ganglioside) immunorecognition in normal skin, cutaneous malignant melanoma (CMM), and in lymph node metastases (LNM) has been previously reported. In this work we extended the study to benign (BMN) and dysplastic (DMN) melanocytic nevi, basal (BCC), and squamous cell carcinoma (SCC). Immunohistochemical assays with 14F7 followed by a biotinylated...

Skin cancer can be categorized into cutaneous melanoma and nonmelanoma skin cancer (NMSC). The latter includes such histologies as Merkel cell carcinoma (MCC), basal cell carcinoma (BCC), and squamous cell carcinoma (SCC). Of these, BCC and SCC are the most common skin cancers of the head and neck while malignant melanoma is the most aggressive. Sunscreen protection and early evaluation of susp...

Basal cell carcinoma (BCC) is the most common non-melanoma skin cancers, Giant variant of BCCs are a rare cutaneous neoplasms. The most important risk factors for skin cancers are ultraviolet (UV) exposure. We report the case of a 69-year-old men presented with pruritus, bleeding, focal ulcerated, large multinodular lesion symptoms and findings in the temporal region of the scalp. Grossly, ther...

introduction ophthalmomyiasis is a rare disorder that is caused by invasion of dipterous larvae to necrotic tissues. case presentation an 80-year-old woman with invasive basal cell carcinoma (bcc) presented anabnormal growth of worm in her eye. she had ophthalmomyiasis caused by lucilia sericata larva in here nucleated eye. l. sericata is common all over the temperate and tropical regions, main...

Merkel cell polyomavirus (MCPyV) has recently been identified in Merkel cell carcinoma (MCC), an aggressive cancer that occurs in sun-exposed skin. Conventional technologies, such as polymerase chain reaction (PCR) and immunohistochemistry, have produced conflicting results for MCPyV infections in non-MCC tumors. Therefore, we performed quantitative analyses of the MCPyV copy number in various ...

Non-melanoma skin cancers (NMSC) are the most common types of cancer and include both basal cell carcinoma (BCC) squamous (SCC). NMSC primarily form on sun exposed including head, face, neck, arms, hands. BCC accounts for >75% cases; however, SCC is more aggressive may occur in other locations as well. Combined, responsible >15,000 deaths each year US alone, which exceed due to melanoma. Curren...