BACKGROUND AND PURPOSE We used quantitative diffusion MR imaging to investigate the microstructural changes that occur in white matter during normal aging in order to identify regional changes in anisotropy and to quantify global microstructural changes by use of whole-brain diffusion histograms. METHODS Full diffusion tensor MR imaging was performed in 20 healthy volunteers, 20 to 91 years o...

an experiment was conducted to determine the aging mechanism in safflower seed using natural aging treatment (storing seed at room temperature for six years) and accelerated aging ( incubating the seed at 41?c and close to 100% relative humidity for 4 ,8 and 12 days). the results indicated that both natural and accelerated aging reduced germination percentage, seed vigor and activity of catalas...

background: aging contains morphological and functional deterioration in biological systems. d-galactose (d-gal) generates free radicals and accelerates aging. portulaca oleracea (purslane) may have protective effect against oxidative stress. objective: purslane ethanolic extract effects were evaluated on antioxidant indices and sex hormone in d-gal aging female mice. materials and methods: 48 ...

This research was conducted to develop a method to identify voice utterance. For voice utterance that encounters change caused by aging factor, with the interval of 10 to 25 years. The change of voice utterance influenced by aging factor might be extracted by MFCC (Mel Frequency Cepstrum Coefficient). However, the level of the compatibility of the feature may be dropped down to 55%. While the o...

The development of medical interventions for the preservation of disease-free longevity would be facilitated by markers that predict healthy aging. Altered protein N-glycosylation patterns have been found with increasing age and several disease states. Here we investigate whether glycans derived from the total glycoprotein pool in plasma mark familial longevity and distinguish healthy from unhe...

The influence of W on the temporal evolution of gamma' precipitation toward equilibrium in a model Ni-Al-Cr alloy is investigated by three-dimensional atom-probe (3DAP) microscopy and transmission electron microscopy (TEM). We report on the alloys Ni-10 Al-8.5 Cr (at.%) and Ni-10 Al-8.5 Cr-2 W (at.%), which were aged isothermally in the gamma + gamma' two-phase field at 1073 K, for times rangin...

The posterior-anterior shift in aging (PASA) is a commonly observed phenomenon in functional neuroimaging studies of aging, characterized by age-related reductions in occipital activity alongside increases in frontal activity. In this work we have investigated the hypothesis as to whether the PASA is also manifested in functional brain network measures such as degree, clustering coefficient, pa...

The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index co...

Twin studies, especially those involving monozygotic (MZ) twins, facilitate the analysis of factors affecting skin aging while controlling for age, gender, and genetic susceptibility. The purpose of this study was to objectively assess various features of facial skin and analyze the effects of environmental factors on these features in MZ twins. At the Osaka Twin Research Center, 67 pairs of MZ...