OBJECTIVE The early diagnosis of (pre)diabetes mellitus is essential for the prevention of diabetes complications. It has been suggested that gum disease (periodontitis) might be an early complication of diabetes and may be a useful risk indicator for diabetes screening. Therefore, a dental office could be a good location for screening for (pre)diabetes in patients with periodontitis using a va...

The purpose of the study was to evaluate the serum level of calcium (Ca) and iron (Fe) in type 2 diabetes mellitus (T2DM) with periodontitis subjects. A total of 450 subjects participated in the study, who were all distributed equally into three groups as control healthy individuals (group I), T2DM without periodontitis (group II), and T2DM with periodontitis (group III), matched for age, sex, ...

Previous studies investigated the association between the IL-6-572C/G polymorphism and chronic periodontitis risk. However, the results were inconclusive. Therefore, we performed this study to assess the association between IL-6-572C/G polymorphism and chronic periodontitis risk. We included 231 patients with chronic periodontitis and 259 healthy controls. IL-6 sequence amplification was done u...

The prevalence of periodontitis is dependent on the studied population and the case definition adopted. Periodontal diseases assume a greater global importance as the senior population is on the rise in most countries. The aim of this article is to review the global prevalence of periodontitis. Studies describing the prevalence of periodontitis in the world were searched through various indices...

Purpose of Review This review describes the recent findings from epidemiological studies on endodontic infections. The recent literature was screened for studies on the prevalence of primary apical periodontitis and posttreatment apical periodontitis in various populations. Recent Findings Twenty-nine articles reporting data on the prevalence of primary or posttreatment apical periodontitis f...

OBJECTIVE Immunological processes in the etiopathogenesis of periodontitis, especially the aggressive form, are not well understood. This study examined clinical as well as systemic immunological and local microbiological features in healthy controls and patients with different forms of periodontitis. MATERIALS AND METHODS 14 healthy subjects, 15 patients diagnosed with aggressive periodontit...

OBJECTIVE The purpose of this study was to investigate the effect of periodontitis on development of overt nephropathy, defined as macroalbuminuria, and end-stage renal disease (ESRD) in type 2 diabetes. RESEARCH DESIGN AND METHODS Individuals residing in the Gila River Indian Community aged > or =25 years with type 2 diabetes, one or more periodontal examination, estimated glomerular filtrat...

BACKGROUND There is a strong evidence that genetic as well as environmental factors affect the age of onset, severity and lifetime risk of developing periodontitis. The objective of the present study was to compare and to evaluate the association between interleukin (IL)-1α(-889) and gene polymorphisms in patients with generalized aggressive periodontitis, chronic periodontitis and healthy cont...

AIM The aim of this study is to investigate the relationship between a vitamin D receptor polymorphism and the diagnosis of periodontal disease in non-smoker Italian patients with aggressive and chronic periodontitis. MATERIALS AND METHODS DNA was obtained from the internal cheek mucosa of 115 patients with chronic periodontitis, 58 with aggressive periodontitis and 65 healthy controls. Allel...

BACKGROUND The periodontal screening index (PSI) is an element of the initial dental examination. The PSI provides information on the periodontal situation and allows a first estimation of the treatment required. The dental panoramic tomography (DPT) indicates the proximal bone loss, thus also allowing conclusions on the periodontal situation. In this study, the results of both methods in deter...