We examined the effect of salbutamol on dry airflow-induced bronchoconstriction (AIB) and acetylcholine-induced bronchoconstriction (Ach-IB) in the canine lung periphery using a wedged bronchoscope technique. Collateral system resistance (Rcs) and airway wall temperature (Taw) were monitored in a peripheral lung segment before, during and after airflow challenge. Rcs before and after aerosolize...

OBJECTIVE To develop a nasal airflow-inducing maneuver and apply it in the olfactory rehabilitation of patients who have undergone laryngectomy. DESIGN Intervention study; before-and-after trial. SETTING National cancer center. PATIENTS Forty-four patients who underwent laryngectomy; 34 men and 10 women; mean age, 64 years (range, 42-80 years); mean time since surgery, 6 years (range, 8 m...

OBJECTIVE The main symptom of lung cancer is dyspnea which can lead to depression, anxiety, limited independent activities, and decreased quality of life. The purpose of this study was to identify the effect of airflow stimulation from a hand-held fan as nonpharmacological palliative intervention on dyspnea in patients with lung cancer. METHODS This study used open, randomized, controlled, cr...

1D3D and 2D2D cyclones were tested at Amarillo, Texas, to evaluate the effect of air density on cyclone performance. Both airflow rate and cyclone inlet velocity change with the change in air density. Two sets of inlet design velocities determined by the different air densities were used for the tests: one set based on the actual airflow, and the other set based on standard airflow. Experimenta...

Obstructive lung diseases in the lower airways are a leading health concern worldwide. To improve our understanding of the pathophysiology of lower airways, we studied airflow characteristics in the lung between the 8th and the 14th generations using a three-dimensional computational fluid dynamics model, where we compared normal and obstructed airways for a range of breathing conditions. We em...

OBJECTIVE Clinical observation has identified cases in which the negative pressures exerted on patient chest drains have appeared to far exceed the level of suction intended. This study was designed to test whether the use of high rates of airflow in typical pleural/mediastinal drainage systems exerts excessively high negative pressures on the chest drainage tube. METHODS Three pleural draina...

The true incidence of chronic obstructive pulmonary disease is largely unknown, because the few longitudinal studies performed have used diagnostic criteria no longer recommended by either the European Respiratory Society or the American Thoracic Society (ATS).We studied the incidence and significance of airflow limitation in a population-based geriatric sample using both an age-dependent predi...

The canine nasal cavity contains hundreds of millions of sensory neurons, located in the olfactory epithelium that lines convoluted nasal turbinates recessed in the rear of the nose. Traditional explanations for canine olfactory acuity, which include large sensory organ size and receptor gene repertoire, overlook the fluid dynamics of odorant transport during sniffing. But odorant transport to ...

OBJECTIVE The aim of this work is to study the hitherto unclear aerodynamic parameters of the pseudo-glottis following total laryngectomy. These parameters include airflow rate, sub-pseudo-glottic pressure (SubPsG), efficiency and resistance, as well as sound pressure level (SPL). PATIENTS AND METHODS Eighteen male patients who have undergone total laryngectomy, with an age range from 54 to 7...