BACKGROUND This study was designed to investigate the effect of a herbal mixture extract (DTS20) on the attenuation of oxidative stress and hangover after alcohol consumption in healthy volunteers. METHODS DTS20 consists of Viscum album L. (40%), Lycium chinense L. (30%), Inonotus obliquus (20%), and Acanthopanax senticosus H. (10%). We recruited healthy, nonsmoking, adult men volunteers aged...

Besides the acute effects of ethanol on a person's performance and behavior, the after-effects of heavy drinking, commonly referred to as the hangover state, causes impairment o f mental and body functioning, such as fatigue, attention deficit, and diminished psychom otor skills (Kelly et al., 1970; Seppala et al., 1976; Lemon et al. 1993). It seems likely that many accidents on the roads and i...

Impaired ethanol metabolism can lead to various alcohol-related health problems. Key enzymes in ethanol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH); however, neuroendocrine pathways that regulate the activities of these enzymes are largely unexplored. Here we identified a neuroendocrine system involving Corazonin (Crz) neuropeptide and its receptor (CrzR) as imp...

Many people seem to have a secret hangover remedy they swear by and many companies are banking on the fact that those "morning after" hangover symptoms can be downright awful. A word to the wise, however: the only real "cure" for a hangover is time. In the meantime, nourishing the body can help to overcome a hangover by treating [2] the symptoms. In terms of that flashy new hangover cure you me...

Many people seem to have a secret hangover remedy they swear by and many companies are banking on the fact that those "morning after" hangover symptoms can be downright awful. A word to the wise, however: the only real "cure" for a hangover is time. In the meantime, nourishing the body can help to overcome a hangover by treating [2] the symptoms. In terms of that flashy new hangover cure you me...